Ribossomo 80S de Eucarionte Flashcards

1
Q

Formação do Ribossomo 80S de Eucarionte - Eventos 3

A

RNApol 1 → transcreve o rRNA 45S

45S → processado em: 18S / 5,8S / 28S

RNApol 3 → transcreve o rRNA 5S

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2
Q

rRNA 5s - Origem

A

RNApol 3

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3
Q

rRNA 45s - Origem

A

RNApol 1

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4
Q

mRNA 45S - Processamento 2

A

Núcleo → clivado por endonucleases

Local de clivagem → introns

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5
Q

mRNA 45S - Produtos da Clivagem 3

A

18S

5,8S

28S

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6
Q

mRNA 45S - Produtos do Processamento 2

A

60S (Maior)

40S (Menor)

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7
Q

mRNA 45S - Processamento

A

Sintetizando no núcleo → clivado → origina os 3 fragmentos (18S / 5,8S / 28S)

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8
Q

Subunidade Maior 60S - Montagem

A

rProteínas: agregamento das → 5,8S / 28S / 5S + ~50 proteínas = montagem da 60S

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9
Q

Subunidade Menor 40S - Montagem

A

rProteinas: agregamento das → 18S / 5,8S + ~30 proteínas = montagem da 40S

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10
Q

rProteínas - Origem

A

Feitas no citoplasma → importadas no núcleo

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11
Q

Subunidade Maior 60S - Composição

A

28S + 5.8S + 5S + ~50 proteínas (L1/L2/L3) = 60S

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12
Q

L1/L2/L3 - Origem do L

A

L de Large

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13
Q

Subunidade Menor 40S - Composição

A

18s + ~33 proteínas (S1/S2/S3) = 40S

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14
Q

Ribossomo 80S de Eucarionte - Origem

A

60S + 40S = 80S

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15
Q

S1/S2/S3 - Origem do S

A

S de Small

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16
Q

S - Origem do Nome / O que é? 3

A

S = unidade de medida da velocidade de sedimentação da molécula na centrífuga

70S sedimenta em 70G (durante centrifugação)

Sivedberg