Rheumatology - Psoriatic Arthritis Flashcards
What is arthritis mutilans?
Complete joint destruction
How long does it usually take for psoriatic arthritis to develop after psoriasis?
Within 10 years
What are the extra-articular manifestations of PA?
Uveitis
IBD
What are the 5 patterns of PA?
Asymmetrical oligoarthritis
1-4 joints
Symmetrical polyarthritis
More than 4 joints affected
DIP predominant pattern
Primarily affects DIPJ
Spondylitis
Axial skeleton
Arthritis mutilans
Osteolysis of bones around joints
Pencil in cup appearance
What are the signs of PA?
Plaques of psoriasis
Nail pitting
Onycholysis
Dactylitis
Enthesitis
What X-ray changes?
Periostitis
Ankylosis
Osteolysis
Dactylitis
Pencil-in-cup appearance
How is PA managed?
NSAIDs
Steroids
DMARDs
Anti-TNF
Ustekinumab- targets IL12 and 23