Cardiology - Valvular Heart Disease Flashcards

1
Q

What causes S1 and S2 heart sounds?

A

S1

Closing of atrioventricular valves at start of systolic contraction

S2

Closing of pulmonary and aortic valves after systolic contraction

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2
Q

What causes a 3rd heart sound?

A

Can indicate heart failure as ventricles and chordae are stiff and weak

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3
Q

When is a third heart sound heard?

A

0.1 seconds after second heart sound

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4
Q

What does a fourth heart sound indicate?

A

Stiff or hypertrophic ventricle

Turbulent flow from atria contracting against non-compliant ventricle

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5
Q

When do you hear a fourth heart sound?

A

Directly before S1

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6
Q

Where is the best point to listen to heart sounds? (S1 and S2)

A

Erb’s point

Third intercostal space left sternal border

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7
Q

What mnemonic should you use to assess a murmur?

A

SCRIPT

Site- where is it loudest

Character- soft/blowing/crescendo etc.

Radiation- heard over carotids or axilla

Intensity- what grade is the murmur

Pitch- high-pitched or low and rumbling

Timing- systolic or diastolic

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8
Q

What are the different murmur grades?

A
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9
Q

How do you present a murmur?

A

ITS RPC
This patient has a harsh / soft / blowing, Grade …, systolic / diastolic murmur

Heard loudest in the aortic / mitral / tricuspid / pulmonary area, that does not / radiates to the carotids / left axilla

It is high / low pitched and has a crescendo / decrescendo / crescendo-decrescendo shape

This is suggestive of a diagnosis of mitral stenosis / aortic stenosis

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10
Q

What is the most common valvular heart disease?

A

Aortic stenosis

Most common indication for valve replacement

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11
Q

Outline aortic stenosis

A

Ejection-systolic
High-pitched
Crescendo-decrescendo

Radiates to carotids

Thrill in aortic area
Slow rising pulse
Narrow pulse pressure
Exertional syncope

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12
Q

What are the causes of aortic stenosis?

A

Age-related calcification

Bicuspid aortic valve

Rheumatic heart disease

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13
Q

Outline aortic regurgitation

(also called Austin-Flint murmur)

A

Early diastolic
Soft murmur

Rumbling murmur

Thrill in aortic area
Collapsing pulse
Wide pulse pressure
Heart failure and pulmonary oedema

Collapsing pulse

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14
Q

What are the causes of aortic regurgitation?

A

Age-related weakness
Bicuspid aortic valve
Ehlers-Danlos syndrome and Marfan syndrome

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15
Q

Outline mitral stenosis

A

Mid-diastolic
Low-pitched rumbling

Tapping apex beat, prominent S1
Malar flush (due to back pressure of blood into pulmonary system, causing a rise in CO2 and vasodilation)
Atrial fibrillation (left atrium struggles to push blood through stenotic valve, causing strain)

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16
Q

What causes mitral stenosis?

A

Rheumatic heart disease
Infective endocarditis

17
Q

Outline mitral regurgitation

A

Reduced ejection fraction
Congestive cardiac failure

Pan-systolic
High-pitched whistling murmur
Radiates to left axilla

Thrill in mitral area
Heart failure and pulmonary oedema signs
AF

18
Q

What causes mitral regurgitation?

A

Ehlers-Danlos syndrome or Marfan syndrome
Age weakening
Ischaemic heart disease
Infective endocarditis
Rheumatic heart disease

19
Q

Outline tricuspid regurgitation

A

Pan-systolic murmur

Split second heart sound due to pulmonary valve closing earlier than aortic as right ventricle empties faster than left ventricle

Thrill in tricuspid area
Raised JVP with giant C-V waves (Lancisi’s sign)
Pulsatile liver (regurgitation into venous system)
Peripheral oedema
Ascites

20
Q

What causes tricuspid regurgitation?

A

Pressure due to left-sided HF or pulmonary hypertension
Infective endocarditis
Rheumatic heart disease
Carcinoid syndrome
Ebstein’s anomaly
Marfan’s syndrome

21
Q

Outline pulmonary stenosis

A

Ejection systolic murmur
Heard loudest with inspiration
Widley split second heart sound as left ventricle empties faster than right ventricle

Thrill in pulmonary area
Raised JVP with giant A waves, right atrium contracts against hypertrophic right ventricle
Peripheral oedema
Ascites

22
Q

What is pulmonary stenosis associated with?

A

Noonan syndrome
Tetralogy of fallot