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Passmed wrong > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Polyarteritis nodosa symptoms

A

fever, malaise, arthralgia
hepatitis symptoms (scleral jaundice, itchiness)
haematuria, purpura (vasculitic signs)

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2
Q

systemic sclerosis with evidence of pulmonary fibrosis (dry cough and SOBOE)

A

diffuse systemic sclerosis

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3
Q

myositis blood marker

A

Anti-Jo1

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4
Q

negative gram stain with elevated WBC (neutrophils)

A

does not rule out septic arthritis

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5
Q

methotrexate toxicity treatment

A

folinic acid

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6
Q

azathioprine and and allopurinol interaction, risk of

A

bone marrow suppression

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7
Q

bone protection if eGFR<30

A

denosumab

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8
Q

Marfans monitoring

A

echocardiogram- aortic aneurysm and dissection

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9
Q

Behcets disease

A

oral ulcers, genital ulcers, uveitis and systemic vasculitis

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10
Q

ank spondylitis second line

A

anti-TNF-alpha blockers e.g. etanercept and infliximab

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11
Q

Tx of renal complications of systemic sclerosis

A

ACEi- captopril

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12
Q

renal complications of systemic sclerosis

A

HTN, AKI
severe- microangiopathic haemolytic anaemia

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13
Q

Hypermobility assessment tool

A

Beighton score

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14
Q

septic arthritis organism in young adults

A

neisseria gonorrhoea

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15
Q

methotrexate drug interaction

A

trimethoprim or co-trimoxazole
–> BM aplasia

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16
Q

osteogenesis imperfects blood test results

A

normal calcium, phosphate, PTH and ALP

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17
Q

What should be corrected before giving bisphosphonates

A

Hypocalcemia/vitamin D deficiency

18
Q

radial tunnel syndrome

A

presents similarly to lateral epicondylitis however, pain distal to epicondyle and worse on elbow extension and forearm pronation

19
Q

Drug induced lupus

A

procainamide
hydralazine
isoniazid
minocycline
phenytoin

20
Q

dermatomyositis association

A

malignancy (ovarian, breast, lung)

21
Q

Schobers test positive

A

<5cm–> reduced lumbar flexion

21
Q

ankylosing spondylitis early sign

A

reduced lateral flexion of lumbar spine
loss of lumbar lordosis, accentuate thoracic kyphosis

22
Q

CKD vs osteomalacia- phosphate

A

low in osteomalacia
high in CKD (2 HPT)

23
Q

psoriatic arthritis management

A

mild peripheral/axial disease –> NSAID
moderate/severe –> methotrexate

ustekinumab, secukinumab

24
Q

osteoporosis risk factors (used in FRAX)

A

history of glucocorticoid use
rheumatoid arthritis
alcohol excess
history of parental hip fracture
low body mass index
current smoking

25
Q

sulfasazline cautions

A

G6PD deficiency, allergy to aspirin or sulphonamides

26
Q

acute flare of RA

A

oral or intramuscular steroids e.g. methylprednisolone

27
Q

ankylosing spondylitis XR spine features

A

squaring of lumbar vertebrae
syndesmophytes
subchondral erosions and sclerosis
bamboo spine (late and uncommon)

28
Q

osteitis fibrosa cystica

A

late stage primary hyperparathyroidism causing excessive bone resorption

29
Q

septic arthritis length of Abx treatment

A

4-6 weeks

30
Q

TNF-alpha s/e

A

reactivation of TB
CXR prior to screen for latent TB

31
Q

polymyalgia rheumatic key investigation

A

raised inflammatory markers- ESR>40

32
Q

discoid lupus erythematous Tx

A

topical steroids –> oral hydroxychloroquine

32
Q

Pagets affects what bones

A

skull, spine/pelvis, long bones of lower extremities

33
Q

CK in PMR

A

normal

34
Q

Measure uric acid levels in suspected gout (i.e. in the acute setting)

A

a uric acid level ≥ 360 umol/L is seen as supporting a diagnosis
if uric acid level < 360 umol/L during a flare repeat the uric acid level measurement at least 2 weeks after the flare has settled

35
Q

when starting allopurinol

A

NSAID or colchicine ‘cover’

36
Q

Lateral epicondylitis- examination

A

worse on resisted wrist extension/suppination whilst elbow extended

37
Q

CKD vs osteomalacia

A

low phosphate= Osteomalacia
high phosphate= CKD

38
Q

reactive arthritis joint aspirate

A

no organism growth on gram stain

develops after an infection where the organism cannot be recovered from the joint

39
Q

SLE: most specific vs most sensitive test

A

most specific= anti-dsDNA
most sensitive= ANA

Passmed wrong (21 decks)

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