CARDIO Flashcards
pharmacological options for treatment of orthostatic hypotension
Fludrocortisone and midodrine
If patients treated with PCI for MI are experiencing pain or haemodynamic instability post PCI
urgent coronary artery bypass graft (CABG) is recommended
causes of raised troponin
Cardio: MI, Aortic dissection, HF, inflammation,
Resp: PE, ARDS
Infectious: SEPSIS
GI: severe GI bleed
Nervous: stroke
Adenosine half life
8-10 seconds
causes of orthostatic hypotension
primary autonomic failure: Parkinson’s disease, Lewy body dementia
secondary autonomic failure: e.g. Diabetic neuropathy, amyloidosis, uraemia
drug-induced: diuretics, alcohol, vasodilators
volume depletion: haemorrhage, diarrhoea
postural hypotension that does not cause an increase in HR VS exaggerated increase in HR
no increase in HR: autonomic dysfunction e.g. DM,
exaggerated increase in HR: anaemia, hypovolemia
mixed aortic valve disease
Bisferiens pulse -
Takayasu’s arteritis symptoms
absent peripheral pulses
uneven blood pressure and pulses between arms
claudication
AR murmur
Takayasu’s arteritis Ix
MR angiogram or CT angiogram
Takayasu’s arteritis associated with
renal artery stenosis
‘non-shockable’ rhythms:
asystole
pulseless-electrical activity
‘shockable’ rhythms:
ventricular fibrillation
pulseless ventricular tachycardia
acute HF management
IV loop diuretics
Nitrates (GTN) if concomitant myocardial ischaemia, severe hypertension or regurgitant aortic or mitral valve disease
‘Global’ T wave inversion
non-cardiac cause e.g. head injury
aortic dissection Ix stable vs unstable
stable- CT angiography
unstable- TOE
Acute heart failure with hypotension
- inotropes be considered for patients with severe left ventricular dysfunction who have potentially reversible cardiogenic shock
elevated JVP, persistent hypotension and tachycardia despite fluid resuscitation in a patient with chest wall trauma
cardiac tamponade
how should adenosine be given in SVT
rapid bolus
loop diuretics electrolyte abnormalities
hyponatraemia
hypokalaemia, hypomagnesaemia
hypocalcaemia
thiazide diuretics electrolyte abnormalities
hypokalaemia
hyponatraemia
hypercalcaemia
blood pressure target for type 2 diabetics:
< 140/90 mmHg
In AF, if a CHA2DS2-VASc score suggests no need for anticoagulation
do an echo to exclude valvular heart disease
S3 causes
heard in left ventricular failure (e.g. dilated cardiomyopathy),
constrictive pericarditis (called a pericardial knock)
mitral regurgitation
Use rhythm control to treat AF if
there is coexistent heart failure, first onset AF or an obvious reversible cause
Moderate-severe aortic stenosis is a contraindication to
ACE-i
irregular broad complex tachycardia in a stable patient
Atrial fibrillation with bundle branch block
raised JVP that doesn’t fall with inspiration
Kussmauls sign
constrictive pericarditis
HF drug which reduced glycemic awareness
beta blocker
intervention of choice for severe mitral stenosis
Percutaneous mitral commissurotomy
digoxin ECG features
down-sloping ST depression (‘reverse tick’, ‘scooped out’)
flattened/inverted T waves
short QT interval
arrhythmias e.g. AV block, bradycardia
Concurrent use of clopidogrel and what drug can make clopidogrel less effective
PPI
polycystic kidney disease associated with what valvular abnormality
mitral valve prolapse
3rd line HF therapy:
ivabradine
sinus rhythm > 75/min and a left ventricular fraction < 35%
3rd line HF therapy:
sacubitril-valsartan
left ventricular fraction < 35%
is considered in heart failure with reduced ejection fraction who are symptomatic on ACE inhibitors or ARBs
should be initiated following ACEi or ARB wash-out period
3rd line HF therapy:
Digoxin
coexistent atrial fibrillation
3rd line HF therapy:
hydralazine in combination with nitrate
Afro-Caribbean
3rd line HF therapy:
cardiac resynchronisation therapy
indications include a widened QRS (e.g. left bundle branch block) complex on ECG
For a person < 80, with stage 1 hypertension ( 135/90 - 149/99) only treat medically if:
diabetic,
renal disease,
QRISK2 >10%,
established coronary vascular disease
end organ damage
contraindications to thrombolysis
active internal bleeding
recent haemorrhage, trauma or surgery (including dental extraction)
coagulation and bleeding disorders
intracranial neoplasm
stroke < 3 months
aortic dissection
recent head injury
severe hypertension
causes of raised BNP other than HF
age over 70 years,
left ventricular hypertrophy, ischaemia,
tachycardia,
right ventricular overload, hypoxaemia (ie pulmonary embolism),
renal dysfunction (eGFR less than 60 ml/minute/1.73 m2),
sepsis,
chronic obstructive pulmonary disease,
diabetes,
or cirrhosis of the liver
arrhythmogenic right ventricular dysplasia ECG
T-wave inversion in leads V1-3 and a terminal notch in the QRS complex (epsilon wave)
Torsade de pointes Tx
IV magnesium sulphate
trifasicular block
RBBB +left anterior or posterior hemiblock + complete heart block