Rheumatology

Question 1

Polymyalgia Rheumatica

Answer 1

Chronic inflammatory disease.

Normally women >50 years

Symmetrical pain in shoulders, hips, or neck; morning stiffness; and systemic symptoms (e.g., fatigue, malaise, and depressed mood).

Tx: prednisolone

Question 2

What does CREST stand for?

Answer 2

Calcinosis cutis, Raynaud phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia.

Question 3

What is CREST syndrome?

Answer 3

A constellation of symptoms in systemic sclerosis.

Question 4

Antibodies in CREST?

Answer 4

Anticentromere antibodies

Question 5

How Sjogren syndrome diagnosed?

Answer 5

Positive antibodies - Anti-Ro/ Anti-La

Salivary gland biopsy

Question 6

Dermatomyositis

Answer 6

Inflammatory myopathy.

Progressive, proximal muscle weakness. Erythematous rash on the extensor hand joints (Gottron sign), upper eyelids (heliotrope rash), upper anterior torso (V-sign), and upper posterior torso (shawl sign).

Anti-Jo1 antibodies