rheumatoid arthritis Flashcards
RA is inflammatory?
yep, expect to see on exam warmth, pain, redness, swelling and loss of function
RA is more common in large or small joints?
small joint
Rheumatoid factor test
IgM ab reactive against the Fc portion of IgG
cyclic citrullinated peptide ab
auto-ab reactive to citrulline, a post-translation modified arginine peptide residue
RA is unilateral or symmetric?
symmetrical
_____ more sensitive may demonstrate erosions much earlier than plain films
US/MRI
primary target in RA
synovium
4> articular
polyarticular
2-3 articular
oligoarticular
treatment of RA should start within
3 months
treatment for RA
use a disease modifying anti-rheumatic drug- methotrexate
complication of RA
felty’s syndrome
polymyalgia rheumatica
occurs over the age of 50, tend with present with morning stiffness and larger joints affected. serology is normal
- temporal artheritis that become blind
