Rheumatic Diseases Flashcards
Characteristics of inflammatory conditions:
- AM vs PM
- Swelling?
- Erythema?
- Warmth?
- Morning stiffness?
- Systemic features?
- Increase in ESR?
- Ex:
Yes, worse in AM Moderate to severe swelling Sometimes present erythema Warmth sometimes present Morning stiffness usually =/> 1 hr Systemic features are sometimes present Frequent inc ESR (erythrocyte sedimentation rate) Ex RA
Characteristics of non-inflammatory conditions:
- AM vs PM
- Swelling?
- Erythema?
- Warmth?
- Morning stiffness?
- Systemic features?
- Increase in ESR?
- Ex:
Pain worse after use Mild swelling Erythema: Often absent Warmth: Absent Morning stiffness usually less than 30 minutes Systemic features: Very rare/absent Uncommon Ex OA
Main feature of rheumatoid arthritis
Synovitis - symmetrical pattern
What is the sequence of events that occurs with synovitis in RA
- Synovium becomes swollen and cells proliferate
- dense cellular membrane (pannus) spreads over articular cartilage
- erodes underlying cartilage and bone
- w/ time: pannus may extend to the opposite articular surface creating:
• fibrous scar tissue
• adhesions
• bony ankylosing`
Synovitis leads to…
- immobility + consolidation (bones form a single unit) of a joint
- bones can become osteopenic
- ligaments/tendons become damaged or ruptured
- surrounding mm deteriorate à joint instability + deformity prone
RA Criteria
- morning stiffness >1hr (6 weeks)
- arthritis of ≥ 3 joints (6weeks)
- arthritis of hand joints
- symmetric arthritis (6weeks)
- rheumatoid nodules
- serum rheumatoid factor
- radiographic changes
- abnormal antibody HLA-DR4 (80% those w/ RA)
Abnormal antibody HLA-DR4 is also found in which populations
Pts with interstitial lung disease, chronic hepatitis, idiopathic pulmonary fibrosis, normal aging adults, SLE
Increased risk of RA w/
o giving birth
o cigarette smoking
o pollution
RA S&S
- pain, fatigue, stiffness (decreased ROM)
- swelling, joint deformity, mm atrophy, extra-articular features
RA Management: Meds
- DMARDs/biologics: stop disease process
- Methotrexate: prevent permanent joint damage/premature death - educate patient on effects on liver and reproductive organs
- NSAIDs, Tylenol, cortisone - don;t stop disease process but reduce inflamm/pain and increase ROM
RA Rehab Acute phase
- energy conservation
- ice
- splints
- gentle ROM
- NO STRETCHING (may stretch the synovial membrane & cause irreversible damage)
RA Rehab Chronic phase
- relieve pain, i.e. modalities, heat
- splints, exercise (gentle ROM)
- relaxation/rest
- Decrease stiffness: gentle ROM
- aquatic ex (endurance exercise)
- functional ex’s
- prevent deformity
- fall prevention
- moderate intensity physical activity
RA lifestyle modifications/self management
- need to be informed, problem solve, self-monitor, and communicate
- education: what the drugs do, what health care team does, resources, exercise and physical activity
RA Surgery
4 R’s • remove (MTP resection) • re-align (tendon rupture) • rest (arthrodesis) • replace (arthroplasty)
What does a joint count assessment tell you
Indicator of RA Disease activity