Rheumatic Diseases Flashcards
Characteristics of inflammatory conditions:
- AM vs PM
- Swelling?
- Erythema?
- Warmth?
- Morning stiffness?
- Systemic features?
- Increase in ESR?
- Ex:
Yes, worse in AM Moderate to severe swelling Sometimes present erythema Warmth sometimes present Morning stiffness usually =/> 1 hr Systemic features are sometimes present Frequent inc ESR (erythrocyte sedimentation rate) Ex RA
Characteristics of non-inflammatory conditions:
- AM vs PM
- Swelling?
- Erythema?
- Warmth?
- Morning stiffness?
- Systemic features?
- Increase in ESR?
- Ex:
Pain worse after use Mild swelling Erythema: Often absent Warmth: Absent Morning stiffness usually less than 30 minutes Systemic features: Very rare/absent Uncommon Ex OA
Main feature of rheumatoid arthritis
Synovitis - symmetrical pattern
What is the sequence of events that occurs with synovitis in RA
- Synovium becomes swollen and cells proliferate
- dense cellular membrane (pannus) spreads over articular cartilage
- erodes underlying cartilage and bone
- w/ time: pannus may extend to the opposite articular surface creating:
• fibrous scar tissue
• adhesions
• bony ankylosing`
Synovitis leads to…
- immobility + consolidation (bones form a single unit) of a joint
- bones can become osteopenic
- ligaments/tendons become damaged or ruptured
- surrounding mm deteriorate à joint instability + deformity prone
RA Criteria
- morning stiffness >1hr (6 weeks)
- arthritis of ≥ 3 joints (6weeks)
- arthritis of hand joints
- symmetric arthritis (6weeks)
- rheumatoid nodules
- serum rheumatoid factor
- radiographic changes
- abnormal antibody HLA-DR4 (80% those w/ RA)
Abnormal antibody HLA-DR4 is also found in which populations
Pts with interstitial lung disease, chronic hepatitis, idiopathic pulmonary fibrosis, normal aging adults, SLE
Increased risk of RA w/
o giving birth
o cigarette smoking
o pollution
RA S&S
- pain, fatigue, stiffness (decreased ROM)
- swelling, joint deformity, mm atrophy, extra-articular features
RA Management: Meds
- DMARDs/biologics: stop disease process
- Methotrexate: prevent permanent joint damage/premature death - educate patient on effects on liver and reproductive organs
- NSAIDs, Tylenol, cortisone - don;t stop disease process but reduce inflamm/pain and increase ROM
RA Rehab Acute phase
- energy conservation
- ice
- splints
- gentle ROM
- NO STRETCHING (may stretch the synovial membrane & cause irreversible damage)
RA Rehab Chronic phase
- relieve pain, i.e. modalities, heat
- splints, exercise (gentle ROM)
- relaxation/rest
- Decrease stiffness: gentle ROM
- aquatic ex (endurance exercise)
- functional ex’s
- prevent deformity
- fall prevention
- moderate intensity physical activity
RA lifestyle modifications/self management
- need to be informed, problem solve, self-monitor, and communicate
- education: what the drugs do, what health care team does, resources, exercise and physical activity
RA Surgery
4 R’s • remove (MTP resection) • re-align (tendon rupture) • rest (arthrodesis) • replace (arthroplasty)
What does a joint count assessment tell you
Indicator of RA Disease activity
3 steps to a RA Joint count
- Joint effusion
- Joint line tenderness
- Stress pain
What 3 joints may get a flexion deformity in RA
Elbow
Hip
Knee
10 common deformities seen with RA
- Hallux valgus
- MTP Subluxation
- Claw toe
- Hammer toe
- mallet toe
- Swan neck
- Boutenniere
- ulnar drift
- Thumb deformities (BD thumb or swan neck)
- DRUJ instability
Features of hallux valgus
- 1st MTP synovitis
- big toe is lateral
- ligament laxity
- erosion
Series of events leading to MTP subluxation
o synovitis, displacement of the flexors, unopposed extensors pull the prox phalanx into hyperext, metatarsal head prolapses and get dislocation and lateral drift of toes
Sign of MTP subluxation
Callouses
Features of claw toe
- MTP synovitis
- MTP ext
- PIP+DIP flex
- often all toes except big toe
Features of hammer toe
MTP and PIP synovitis
- usually involves 2nd toe
- flex of PIP and hyperext of DIP (similar to boutonniere)
Features of mallet toe
- Flex of DIP
- affects longest toe