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finals > Rheum > Flashcards

Rheum Flashcards

1
Q

ankolosing spondolitis the features - the As (6)

A

Apical fibrosis
Anterior uveitis
Aortic regurgitation
Achilles tendonitis
AV node block
Amyloidosis

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1
Q

MC cardiac manifestation of SLE

A

pericarditis

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2
Q

acne vulgaris tx in pregnancy

A

use erthromycin + topical azaeilic acid

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3
Q

venous ulceration where

A

medieal malleolus

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4
Q

how to asses burns

A

Lund and browder chart

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5
Q

gastric adenocarcinoma skin presentation

A

acanthosis nicragans

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6
Q

ANA

A

SLE

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7
Q

Rheumatoid factr

A

RA

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8
Q

Anti-ccp

A

RA

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9
Q

DS-DNA

A

lupus and lupus nephritis

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10
Q

Anti histone

A

lupus and drug induced lupus

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11
Q

Centromere ABs

A

scleroderma (crest)

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12
Q

Topoisomerase SCL-70

A

scleroderma (systemic SSc)

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13
Q

smooth muscle ABs

A

autoimmnune hepatitis

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14
Q

RO+LA ABs

A

sjorgens

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15
Q

JO Abs

A

poly/dermatomyositosis

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16
Q

anti mitochondrial ABs

A

primary bilary cirrhosis

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17
Q

anti smith

A

Lupus SLE

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18
Q

SLE more common in

A

black &
women

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19
Q

SLE symptoms MDSOAP BRAIN

A

Malar rash
Discoid rash
Serositis
Oral Ulcer
Arthritis
Photosensitivity

Blood (low Hb and plts)
Renal Failure (lupus nephritis)
ANA +ve
Immunologic
Neuro

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20
Q

why may 1st trimester loss be sx of SLE

A

might have antiphospholipid syndrome which is associated w SLE

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21
Q

Drug induced lupus cause and sx and danger

A

mc hydralazine
Painful rash post new drug w serositis and arthritis

remove agent doesnt cause neuro or nephritis so not life threateneing

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22
Q

how to tell between SLE flare and infection

A

check complement level

(low in flare)

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23
Q

gout athrocentisis

A

-ve bifingent
needle shaped

yellow laser on histo

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24
Q

pseudogout athrocentisis

A

=ve bifringent
rhombid crystals

25
Q

long term gout tx if want to lower uric acid levels

A

allopurinoll

26
Q

long term gout tx if want to prevent flares

A

colchicine

27
Q

Septic joint tx

A

IV ABX 2 weeks then PO 2-4wks

staph = fluclox
Mrsa = Vanc
Gonorhea / gram -ve bacilli = cefotaxime

+ if also has chlamydia = doxy/azithro

28
Q

autimmune vs spondloarthrop usually in who

A

autoimmune = women

spond = men

29
Q

charcots joint what is it

who gets it

A

neuropathic joint

loss of sensation = joint damage disruption and remodelling

used to be syphillis but now diabetics

30
Q

when to start urate lowering therapy in Gout
(allopurinol/febuxostat) and for who

A

2 weeks post flare

first attack
>2 attacks in yr
tophi
renal disease
uric acid renal stones
proph if on cytoxics/diuretics

31
Q

periarticular erosions XR

A

rheumatid arth

32
Q

ankylosing spondylitis plain XR

A

formation of bridging Syndesmophytes (ossification of outer fibres of annulus fibrosus)
= bamboo spine

calc of intervert ligaments
fusion of spinal facet joints

33
Q

Pseudogout XR

A

chondrocalcinosis

Calciumpyrophosdisease (CPPD)= deposition in cartilagneous tissue

34
Q

young adult sexually active septic arthritis MC organism and gram stain

A

neiserria gonor

gram -ve
diplococci

35
Q

ank spond XR

A

sunchondral erosions, sclerorosis
verterbral squaring

36
Q

4 signs of infective flexor tenosynovitis (tendon sheath infection)

what are they called

A

fixed flexion,
fusiform swelling,
tenderness
pain on passive extension

Kanavels sign

37
Q

adult onset stills disease presentation

A

pyrexia arthralgia rash
lymphadenopathy

fever rises in early evening everyday accompany worsening of joint sx and rash

rash salmon pink maculopapular on turnk arms and legs

elevated ferritin
RF and ANA negative

38
Q

adult onset stills disease dx criteria

A

yamaguchi

39
Q

management of stills

A

NSAIDS
the steroids

if still sx maybe methtrex, IL1 or anti TNF

40
Q

pseudogout path

A

deposition of calcium pyrophosphate dihydrate crystals in the synovium

41
Q

causes of pseudogout in someone younger than 60

A

haemochromatosis
hyperparathyroidism
low mag low phos
acromegaly
wilsons

42
Q

sjorgrens test

A

shirmers test: filter paper near conjunctival sac to measure tear formation

43
Q

PMR tx

A

pred 15mg od

44
Q

RA early XR findings

A

loss of joint space
juxta-articular osteoporosis
soft tissue swelling
periarticular erosions
subluxation

45
Q

RA hand deformatyes

A

joint swelling

swan neck
boutonierre
z shaped thumb
ulnar deviation

46
Q

extraarticular fx of RA

A

scleritis
episcleritis
carpal tunnel
raynauds
pericardial/pleural effusion
pul.fibrosis

47
Q

felty syndrome triad

A

RA
neutropenia
splenomegaly

48
Q

methotrexate how and ofetn

A

oral/IM

weekly

49
Q

HLAB27 diseases

A

psoriatic arthritis
ank spond
IBD

50
Q

limites sysem scleoris s

ab

A

CREST

calcinosis
raynauds
esophageal gut dysmotlity
sclerodactyly
talenectalasia

anti centromere

51
Q

diffuse systemic sclerosis sx

sb

A

gord, asp, dysphagia
lung fib and htn
artythmia
acute hypertesive crisis (renal) mc cause of death

52
Q

polyand dermyositosus
path and pt

often what

A

straited muscle inflammation
progressive symmetircal proximal weaknesss
wasting og shoulder and pelvic girdle
dysphonia, dyspagua resp weakness

paraneoplastic
lung panc ovarian bowel

53
Q

anti phospholipid abs

A

anti phosphilid
anti cardiolipin

54
Q

anti phos lipid fx

A

CLOTS

coag defect - inc APTT vte and arterial ie stroke
livedi reticularis
obstetric complications - recurrent 1st tri misscar
thrombocytopenia

55
Q

large cell vasc

A

GCA
takayasu

56
Q

medium vessal vasc

A

polyartertis nodusa
kawasaki

57
Q

small vessal vasc

A

p anca (churgstrauss, micropolyang)

c anca (wegener gran)

ANCA -ve
- henolch purp
- goodpastur
cryoglobuneama
cutaous leukocytic basc

58
Q

PMR bloods

A

v high ESR (n crp)
inc ALP
Inc plasma visc

NORMAL CK

59
Q

polyarteritis nodusa

A

assx hep B

rash renal ->htn
GIt - malana and abdo pain

pred and cyclophosphomide

60
Q
A

finals (28 decks)

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