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Rheum Flashcards

1
Q

ankolosing spondolitis the features - the As (6)

A

Apical fibrosis
Anterior uveitis
Aortic regurgitation
Achilles tendonitis
AV node block
Amyloidosis

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1
Q

MC cardiac manifestation of SLE

A

pericarditis

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2
Q

acne vulgaris tx in pregnancy

A

use erthromycin + topical azaeilic acid

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3
Q

venous ulceration where

A

medieal malleolus

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4
Q

how to asses burns

A

Lund and browder chart

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5
Q

gastric adenocarcinoma skin presentation

A

acanthosis nicragans

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6
Q

ANA

A

SLE

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7
Q

Rheumatoid factr

A

RA

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8
Q

Anti-ccp

A

RA

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9
Q

DS-DNA

A

lupus and lupus nephritis

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10
Q

Anti histone

A

lupus and drug induced lupus

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11
Q

Centromere ABs

A

scleroderma (crest)

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12
Q

Topoisomerase SCL-70

A

scleroderma (systemic SSc)

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13
Q

smooth muscle ABs

A

autoimmnune hepatitis

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14
Q

RO+LA ABs

A

sjorgens

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15
Q

JO Abs

A

poly/dermatomyositosis

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16
Q

anti mitochondrial ABs

A

primary bilary cirrhosis

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17
Q

anti smith

A

Lupus SLE

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18
Q

SLE more common in

A

black &
women

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19
Q

SLE symptoms MDSOAP BRAIN

A

Malar rash
Discoid rash
Serositis
Oral Ulcer
Arthritis
Photosensitivity

Blood (low Hb and plts)
Renal Failure (lupus nephritis)
ANA +ve
Immunologic
Neuro

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20
Q

why may 1st trimester loss be sx of SLE

A

might have antiphospholipid syndrome which is associated w SLE

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21
Q

Drug induced lupus cause and sx and danger

A

mc hydralazine
Painful rash post new drug w serositis and arthritis

remove agent doesnt cause neuro or nephritis so not life threateneing

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22
Q

how to tell between SLE flare and infection

A

check complement level

(low in flare)

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23
Q

gout athrocentisis

A

-ve bifingent
needle shaped

yellow laser on histo

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24
pseudogout athrocentisis
=ve bifringent rhombid crystals
25
long term gout tx if want to lower uric acid levels
allopurinoll
26
long term gout tx if want to prevent flares
colchicine
27
Septic joint tx
IV ABX 2 weeks then PO 2-4wks staph = fluclox Mrsa = Vanc Gonorhea / gram -ve bacilli = cefotaxime + if also has chlamydia = doxy/azithro
28
autimmune vs spondloarthrop usually in who
autoimmune = women spond = men
29
charcots joint what is it who gets it
neuropathic joint loss of sensation = joint damage disruption and remodelling used to be syphillis but now diabetics
30
when to start urate lowering therapy in Gout (allopurinol/febuxostat) and for who
2 weeks post flare first attack >2 attacks in yr tophi renal disease uric acid renal stones proph if on cytoxics/diuretics
31
periarticular erosions XR
rheumatid arth
32
ankylosing spondylitis plain XR
formation of bridging Syndesmophytes (ossification of outer fibres of annulus fibrosus) = bamboo spine calc of intervert ligaments fusion of spinal facet joints
33
Pseudogout XR
chondrocalcinosis Calciumpyrophosdisease (CPPD)= deposition in cartilagneous tissue
34
young adult sexually active septic arthritis MC organism and gram stain
neiserria gonor gram -ve diplococci
35
ank spond XR
sunchondral erosions, sclerorosis verterbral squaring
36
4 signs of infective flexor tenosynovitis (tendon sheath infection) what are they called
fixed flexion, fusiform swelling, tenderness pain on passive extension Kanavels sign
37
adult onset stills disease presentation
pyrexia arthralgia rash lymphadenopathy fever rises in early evening everyday accompany worsening of joint sx and rash rash salmon pink maculopapular on turnk arms and legs elevated ferritin RF and ANA negative
38
adult onset stills disease dx criteria
yamaguchi
39
management of stills
NSAIDS the steroids if still sx maybe methtrex, IL1 or anti TNF
40
pseudogout path
deposition of calcium pyrophosphate dihydrate crystals in the synovium
41
causes of pseudogout in someone younger than 60
haemochromatosis hyperparathyroidism low mag low phos acromegaly wilsons
42
sjorgrens test
shirmers test: filter paper near conjunctival sac to measure tear formation
43
PMR tx
pred 15mg od
44
RA early XR findings
loss of joint space juxta-articular osteoporosis soft tissue swelling periarticular erosions subluxation
45
RA hand deformatyes
joint swelling swan neck boutonierre z shaped thumb ulnar deviation
46
extraarticular fx of RA
scleritis episcleritis carpal tunnel raynauds pericardial/pleural effusion pul.fibrosis
47
felty syndrome triad
RA neutropenia splenomegaly
48
methotrexate how and ofetn
oral/IM weekly
49
HLAB27 diseases
psoriatic arthritis ank spond IBD
50
limites sysem scleoris s ab
CREST calcinosis raynauds esophageal gut dysmotlity sclerodactyly talenectalasia anti centromere
51
diffuse systemic sclerosis sx sb
gord, asp, dysphagia lung fib and htn artythmia acute hypertesive crisis (renal) mc cause of death
52
polyand dermyositosus path and pt often what
straited muscle inflammation progressive symmetircal proximal weaknesss wasting og shoulder and pelvic girdle dysphonia, dyspagua resp weakness paraneoplastic lung panc ovarian bowel
53
anti phospholipid abs
anti phosphilid anti cardiolipin
54
anti phos lipid fx
CLOTS coag defect - inc APTT vte and arterial ie stroke livedi reticularis obstetric complications - recurrent 1st tri misscar thrombocytopenia
55
large cell vasc
GCA takayasu
56
medium vessal vasc
polyartertis nodusa kawasaki
57
small vessal vasc
p anca (churgstrauss, micropolyang) c anca (wegener gran) ANCA -ve - henolch purp - goodpastur cryoglobuneama cutaous leukocytic basc
58
PMR bloods
v high ESR (n crp) inc ALP Inc plasma visc NORMAL CK
59
polyarteritis nodusa
assx hep B rash renal ->htn GIt - malana and abdo pain pred and cyclophosphomide
60

finals (28 decks)

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