Rheum Flashcards
ankolosing spondolitis the features - the As (6)
Apical fibrosis
Anterior uveitis
Aortic regurgitation
Achilles tendonitis
AV node block
Amyloidosis
MC cardiac manifestation of SLE
pericarditis
acne vulgaris tx in pregnancy
use erthromycin + topical azaeilic acid
venous ulceration where
medieal malleolus
how to asses burns
Lund and browder chart
gastric adenocarcinoma skin presentation
acanthosis nicragans
ANA
SLE
Rheumatoid factr
RA
Anti-ccp
RA
DS-DNA
lupus and lupus nephritis
Anti histone
lupus and drug induced lupus
Centromere ABs
scleroderma (crest)
Topoisomerase SCL-70
scleroderma (systemic SSc)
smooth muscle ABs
autoimmnune hepatitis
RO+LA ABs
sjorgens
JO Abs
poly/dermatomyositosis
anti mitochondrial ABs
primary bilary cirrhosis
anti smith
Lupus SLE
SLE more common in
black &
women
SLE symptoms MDSOAP BRAIN
Malar rash
Discoid rash
Serositis
Oral Ulcer
Arthritis
Photosensitivity
Blood (low Hb and plts)
Renal Failure (lupus nephritis)
ANA +ve
Immunologic
Neuro
why may 1st trimester loss be sx of SLE
might have antiphospholipid syndrome which is associated w SLE
Drug induced lupus cause and sx and danger
mc hydralazine
Painful rash post new drug w serositis and arthritis
remove agent doesnt cause neuro or nephritis so not life threateneing
how to tell between SLE flare and infection
check complement level
(low in flare)
gout athrocentisis
-ve bifingent
needle shaped
yellow laser on histo
pseudogout athrocentisis
=ve bifringent
rhombid crystals
long term gout tx if want to lower uric acid levels
allopurinoll
long term gout tx if want to prevent flares
colchicine
Septic joint tx
IV ABX 2 weeks then PO 2-4wks
staph = fluclox
Mrsa = Vanc
Gonorhea / gram -ve bacilli = cefotaxime
+ if also has chlamydia = doxy/azithro
autimmune vs spondloarthrop usually in who
autoimmune = women
spond = men
charcots joint what is it
who gets it
neuropathic joint
loss of sensation = joint damage disruption and remodelling
used to be syphillis but now diabetics
when to start urate lowering therapy in Gout
(allopurinol/febuxostat) and for who
2 weeks post flare
first attack
>2 attacks in yr
tophi
renal disease
uric acid renal stones
proph if on cytoxics/diuretics
periarticular erosions XR
rheumatid arth
ankylosing spondylitis plain XR
formation of bridging Syndesmophytes (ossification of outer fibres of annulus fibrosus)
= bamboo spine
calc of intervert ligaments
fusion of spinal facet joints
Pseudogout XR
chondrocalcinosis
Calciumpyrophosdisease (CPPD)= deposition in cartilagneous tissue
young adult sexually active septic arthritis MC organism and gram stain
neiserria gonor
gram -ve
diplococci
ank spond XR
sunchondral erosions, sclerorosis
verterbral squaring
4 signs of infective flexor tenosynovitis (tendon sheath infection)
what are they called
fixed flexion,
fusiform swelling,
tenderness
pain on passive extension
Kanavels sign
adult onset stills disease presentation
pyrexia arthralgia rash
lymphadenopathy
fever rises in early evening everyday accompany worsening of joint sx and rash
rash salmon pink maculopapular on turnk arms and legs
elevated ferritin
RF and ANA negative
adult onset stills disease dx criteria
yamaguchi
management of stills
NSAIDS
the steroids
if still sx maybe methtrex, IL1 or anti TNF
pseudogout path
deposition of calcium pyrophosphate dihydrate crystals in the synovium
causes of pseudogout in someone younger than 60
haemochromatosis
hyperparathyroidism
low mag low phos
acromegaly
wilsons
sjorgrens test
shirmers test: filter paper near conjunctival sac to measure tear formation
PMR tx
pred 15mg od
RA early XR findings
loss of joint space
juxta-articular osteoporosis
soft tissue swelling
periarticular erosions
subluxation
RA hand deformatyes
joint swelling
swan neck
boutonierre
z shaped thumb
ulnar deviation
extraarticular fx of RA
scleritis
episcleritis
carpal tunnel
raynauds
pericardial/pleural effusion
pul.fibrosis
felty syndrome triad
RA
neutropenia
splenomegaly
methotrexate how and ofetn
oral/IM
weekly
HLAB27 diseases
psoriatic arthritis
ank spond
IBD
limites sysem scleoris s
ab
CREST
calcinosis
raynauds
esophageal gut dysmotlity
sclerodactyly
talenectalasia
anti centromere
diffuse systemic sclerosis sx
sb
gord, asp, dysphagia
lung fib and htn
artythmia
acute hypertesive crisis (renal) mc cause of death
polyand dermyositosus
path and pt
often what
straited muscle inflammation
progressive symmetircal proximal weaknesss
wasting og shoulder and pelvic girdle
dysphonia, dyspagua resp weakness
paraneoplastic
lung panc ovarian bowel
anti phospholipid abs
anti phosphilid
anti cardiolipin
anti phos lipid fx
CLOTS
coag defect - inc APTT vte and arterial ie stroke
livedi reticularis
obstetric complications - recurrent 1st tri misscar
thrombocytopenia
large cell vasc
GCA
takayasu
medium vessal vasc
polyartertis nodusa
kawasaki
small vessal vasc
p anca (churgstrauss, micropolyang)
c anca (wegener gran)
ANCA -ve
- henolch purp
- goodpastur
cryoglobuneama
cutaous leukocytic basc
PMR bloods
v high ESR (n crp)
inc ALP
Inc plasma visc
NORMAL CK
polyarteritis nodusa
assx hep B
rash renal ->htn
GIt - malana and abdo pain
pred and cyclophosphomide
