Rheum Flashcards

1
Q

Kawasaki disease labs

A

Platelets and WBCs up; hemoglobin down
AST and ALT up
Sterile pyuria
Acute-phase reactants up

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2
Q

Kawasaki treatment

A

IVIG
Aspirin

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3
Q

Kawasaki complications

A

Coronary artery aneurysms
Ventricular dysfunction (due to inflammation or lymphocytic myocarditis)
Pericardial effusion –> cardiac tamponade

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4
Q

Langerhans cell histiocytosis treatment

A

Chemotherapy (prednisone +/- vinblastine)
Desmopressin for diabetes insipidus

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5
Q

Langerhans cell histiocytosis pathogenesis

A

Macrophages within tissue proliferate and infiltrate:
Lytic bone lesions (skull, femur, others) with overlying skin lesion
Purplish papules, eczematous rash
Pulmonary cysts/nodules
LAD, hepatosplenomegaly
Central diabetes insipidus

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6
Q

Bone pain at night that resolves with NSAIDs in an adolescent suggests…

A

Osteoid osteoma - small, round hypodensity with sclerotic border on x-ray

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7
Q

Sarcoidosis shows what kind of granulomas?

A

Noncaseating

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8
Q
A
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9
Q

Child with gout and inexplicable injuries

A

Lesch-Nyhan syndrome - hypoxanthine-guanine phosphoribosyltransferase deficiency

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