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Blood Bank - review > Rh blood group system > Flashcards

Rh blood group system Flashcards

1
Q

2nd most important blood group in transfusion

A

Rh

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2
Q

Rh antigen is capable of causing

A

HDFN and HTR

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3
Q

Discovered by

A

Levine and Stetson

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4
Q

phenotypically related to Rh blood group system

A

Anti-LW

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5
Q

Persons with extremely low D antigens

A

Del

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6
Q

parts of D antigen are missing

A

D mosaic / Partial D

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7
Q

Position of C affects the D

A

C in trans to RHD

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8
Q

Degree of antigenicity

A

D > c > E > C > e

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9
Q

antigens were produced by three closely linked sets of alleles

A

Fisher-Race: DCE Terminology

eg. DCe

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10
Q

multiple allelic genes in single locus

A

Wiener: Rh-Hr terminology

eg. rh’hr”

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11
Q

z and y represents

A

C and E together

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12
Q

D, C, E, c, e are represented by Rh 1, 2, 3, 4, 5

A

Rosenfield: Alphanumeric terminology

eg. Rh 1, 2, 3, 4, 5

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13
Q

adopted 6-digit number for each antigen belonging to blood group system

A

International Society of Blood Transfusion (ISBT)

eg. 004001

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14
Q

TEST FOR WEAK D

A

Indirect AHG/Coomb’s test

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15
Q

how is weak D Px reported

A

patient: typed as Rh (-)
donor: Rh (+)

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16
Q

Rh null associated

A

Hereditary spherocytosis

17
Q

antigen present on most D-positive and all C-positive RBCs

•

A

G

18
Q

the destruction of the red blood cells (RBCs) of a fetus and neonate by antibodies produced by the

A

Ab produced by the mother

19
Q

occurs when maternal IgG attaches to specific antigens of the fetal RBCs

A

hemolysis

20
Q

Destruction of red cells

A

anemia

21
Q

Increased production of red cells

A

erythropoiesis

22
Q

ighly specialized prenatal test in which a sample of the baby’s blood is removed from the
umbilical cord for testing.

A

cordocentesis

23
Q

volume of fetal blood that can immunize the mother

A

1 ml

Blood Bank - review (7 decks)

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