RH BLOOD GROUP SYSTEM

Question 1

What ISBT does RH blood group system belong?

Answer 1

ISBT no. 004

Question 2

They discovered the RH antigen in serum of obstetrical patient who received blood transfusion from her husband after delivering a dead baby.

Answer 2

Levine and Stetson

Question 3

Rh antigen was named by these two

Answer 3

Landsteiner and Weiner

Question 4

Rh antigen was discovered in which type of animal?

Answer 4

Rhesus Macaque monkey

Question 5

What is the difference between RH positive snd RH negative?

Answer 5

RH positive- has the presence of D antigen (D)
RH negative- absence of D antigen (d)

Question 6

In this terminology, each Rh genes are inherited from each parent as a set of 3 closely linked sets of alleles

Answer 6

Fischer-Race Terminology

Question 7

In this terminology, each Rh gene encodes for an agglutinogen that contains a series of 3 blood factors/antigens

Answer 7

Wiener Terminology

Question 8

Rh genes are always expressed as?

Answer 8

Codominant

Question 9

Wiener terminology is also known as

Answer 9

Rh-Hr Nomenclature

Question 10

DCE nomenclature is used for what terminology?

Answer 10

Fischer-Race Terminology

Question 11

It is also known as the Alpha-Numeric Nomenclature

Answer 11

Rosenfield & Coworkers Terminology

Question 12

ISBT Terminology is also known as

Answer 12

Numeric Nomenclature

Question 13

Which chromosome do RHD and RHCE genes belong?

Answer 13

Chromosome 1

Question 14

Which chromosome do RHAG/X1r genes belong?

Answer 14

Chromosome 6

Question 15

It is the regulator type of Rh null

Answer 15

XOr

Question 16

It is the Rh mod phenotype which partially suppress antigen expression

Answer 16

XQr

Question 17

Silent type of Rh null

Answer 17

little r double bar

Question 18

What are the 2 types of RH Null Phenotype

Answer 18

Silent and Regulator Type

Question 19

It is a type of Rh Null Phenotype in which it is due to the inheritance of little r double bar

Answer 19

Silent Type

Question 20

Regulator type of Rh null is due to the inheritance of what gene?

Answer 20

XOrXOr

Question 21

Hemoglobin and Hematocrit is _________ in Regulator type

Answer 21

Decreased

Question 22

Bilirubin and Hemoglobin F is _________ in Regulator type

Answer 22

Increased

Question 23

What type of antigen expression has small amount of D antigen with missing parts of fragments

Answer 23

Du Type

Question 24

Du Type expresses as Rh Negative
T or F

Answer 24

False
Du Type is Rh positive and needs to be tested by AHG Test to demonstrate presence

Question 25

Causes/Mechanisms

Answer 25

Genetic Weak D
C-trans
Mosaic/Partial D/D variant/Categories of D
Del Phenotype

Question 26

Most Rh antigens react in what temperature?

Answer 26

37C

Question 27

What Immunoglobulin is Rh antibodies mostly related

Answer 27

IgG

Question 28

It is the most immunogenic type of antigen

Answer 28

D antigen

Question 29

How many days do Rh antibodies be produced after primary exposure?

Answer 29

120 days

Question 30

How many days will Rh antibodies be produced after secondary exposure?

Answer 30

2-7 days

Question 31

Do Rh antibodies bind to complement?

Answer 31

No, because it needs 2 IgG immunoglobulins to attach in an RBC close proximity