OTHER BLOOD GROUP SYSTEM: WARM ACTING

Question 1

In Private settings what type of incident is present?

Answer 1

High Incident

Question 2

What antigens are related in High Incident groups?

Answer 2

k (cellano)
e

Question 3

What antigens are related in Low Incident groups?

Answer 3

K (cell)

Question 4

What type of Ig is clinically significant because of the association with decreased RBC survival

Answer 4

IgG

Question 5

What type of Ig is not clinically significant as it does not cause red cell destruction

Answer 5

IgM

Question 6

What are the functional roles of Other Blood Group system

Answer 6

Glycosyltransferases
Structural Relationship to the RBC
Transport Proteins
Complement Pathway molecules
Adhesion molecules
Microbial receptors
Biologic receptors

Question 7

What type of RBC cell is related to Gerbich Null

Answer 7

Elliptocytosis

Question 8

What reagent destroys an enzyme in Kell BGS

Answer 8

Sulfhydryl reagent

Question 9

What are the 2 most common types of Kell BGS

Answer 9

Kell (Low Incident)
Cellano (High Incident)

Question 10

Which Chromosome is Kell BGS located in?

Answer 10

Chromosome 7

Question 11

Kell antigens can be destroyed by which reagent

Answer 11

Glycine-acid EDTA

Question 12

Where does Kell antigens covalently linked?

Answer 12

Kx antigen (019)

Question 13

No expression of Kell antigens is called?

Answer 13

Kell Null

Question 14

What Ig react well in AHG Test of Kell BGS

Answer 14

IgG

Question 15

What type of antigen is most common in Kell BGS due to its immunogenicity?

Answer 15

Anti-K

Question 16

Which chromosome does Kx antigen located?

Answer 16

Chromosome X

Question 17

T or F
Kx antigen is bound directly to red cell, and helps in binding Kell to red cell

Answer 17

True

Question 18

What are the 3 antigens of Kidd BGS

Answer 18

Jka
Jkb
Jk

Question 19

In which chromosome is Kidd BGS located

Answer 19

Chromosome 18

Question 20

Which Jk phenotype is most common in Filipinos

Answer 20

Jk Null
Jk (a-b-)

Question 21

Kidd Antigens are believed to be _________ Transporter

Answer 21

Urea

Question 22

Kidd antigen is well developed on how many days

Answer 22

11 weeks

Question 23

Kidd antibodies binds to complement
T or F

Answer 23

True

Question 24

Kidd antibodies are the most common cause of what type of disease?

Answer 24

Hemolytic Transfusion Reaction

Question 25

What bacteria have Jkb-like specificity that may interfere with the result of tests

Answer 25

Micrococcus and Enterococcus faecium

Question 26

This bacteria produces autoanti-Jkb

Answer 26

Proteus mirabilis

Question 27

This enzyme together with sulfhydryl reagent can destroy Duffy antigens

Answer 27

Papain and Ficin

Question 28

Duffy BGS is located in which chromosome?

Answer 28

Chromosome 1

Question 29

What are the 2 types of antigen in Duffy BGS

Answer 29

Fya and Fyb

Question 30

What is the phenotype of persons resistant to malaria for Duffy BGS

Answer 30

Fy (a-b-)

Question 31

What Duffy antigen is resistant to enzymes?

Answer 31

Fyb and Fy3

Question 32

What Duffy antigen is the receptor of P. vivax and P. knowlesi

Answer 32

Fy6

Question 33

Duffy antibodies has no immediate cell lysis hence;

Answer 33

not capable of complement binding

Question 34

What Duffy antigen will not be invaded by P. vivax and P. knowlesi

Answer 34

Fya and Fyb

Question 35

What are the 2 types of Lutheran antigen

Answer 35

Lua and Lub

Question 36

What are the obsolete type of Lutheran Antigen

Answer 36

Lu10 and Lu15

Question 37

How many antigens are there in Lutheran BGS

Answer 37

20 + 2 obsolete

Question 38

It is the silent gene of Lutheran BGS

Answer 38

Lu gene

Question 39

It is the regulator gene of Lutheran BGS

Answer 39

In(Lu) gene