Reward Systems & Drug addiction

Question 1

What are 3 relapse triggers?

Answer 1

Emotional
Environmental
Expsoure

Question 2

What is addiction?

Answer 2

1) risk use
2) Pharmological tolerance

3)

Question 3

Drug addiction pathway

Answer 3

brain has a natrual reward mechanisms (mesolimbic dopamine)

Question 4

Cocaine

Answer 4

You get a rush of dopamine, the brain is going to make changes to cope, it needs more receeptors to process excess dopamine, so more recepots pop up

Question 5

Cocaine

Answer 5

You get a rush of dopamine, the brain is going to make changes to cope, it needs more receeptors to process excess dopamine, so more receptors pop up. So next time you have food, all these extra receptors are not binding to anything.Food is no longer rewarding. so now you have this craving to fufill these extra bindings w dopamine.

Question 6

Cocaine mechanisms

Answer 6

everything that cocaine releases stays there, it blocks the reuptake of dopamine so it stays longer in the synpases!!! Its binding to the receptors multiple times. Usually it falls off, but since its staying in the receptors i binds mutlipe times.

Question 7

Drug addiciton & strong memories

Answer 7

Drug asscociated cues make a very strong memories that are almost impossible to remove even with extinction

Question 8

Extinction- what is it actually

Answer 8

Giving them the cue but not giving the reward
- its only temporary
-it doesn’t remove the association/ you cant undo the og memory, its simply making a new memory that masks the old memory!!
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Question 9

Treatment Approaches

Answer 9

-Re-consolidation: stable memories become suscpitlbe to change every time they are retrieved.
-hypothetical process every time you retrieved that memory.
-what if you can have ppl retrieve memory disrupt it while its online.
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