Brain Cell Communication Jan 21 Flashcards

1
Q

What is the resting membrane potential?

A

-70mV

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2
Q

What are some of the forces that affect the action potential?

A

Diffusion, Electrostatic pressure, & Sodium/Potassium pumps

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3
Q

Is Potassium (K+) higher inside the cell or outside the cell?

A

Higher inside the cell

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4
Q

How do the forces move Potassium (K+) in and out the cell?

A

Diffusion forces it outside; electrostatic pressure forces it inside.

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5
Q

How does the membrane stay at resting potential?

A

Diffusion, electrostatic pressure, & Sodium potassium pump

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6
Q

Diffusion

A

hi to low concentration

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7
Q

Electrostatic pressure

A

similarly charged ions repel each other (all positives will move away)

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8
Q

What is depolarization?

A

The rapid shift from negative to positive of the membrane potential

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9
Q

What is repolarization?

A

After the peak of depolarization, the cell begins returning to negative potential

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10
Q

Depolariazation

A

Sodium rushing in

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11
Q

Is Sodium (Na+) higher inside the cell or outside the cell?

A

Higher outside the cell.

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12
Q

How do the forces move Sodium (Na+) in and out of the cell?

A

Diffusion forces it inside; Electrostatic pressure forces it inside.

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13
Q

Sodium/Potassium pump

A

Returns membrane back to rest (-70mV); is always on

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14
Q

What is depolarization?

A

The rise of membrane potential

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15
Q

What is hyperpolarization?

A

Helps balance the negative back to resting potential

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16
Q

What causes depolarization?

A

When a threshold of -55mV is met, voltage Na+ channels open; Na+ rush in

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17
Q

When do the K+ channels open and close?

A

Always after the Na+ channels open or close; K+ exits the cell

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18
Q

What happens when depolarization ends?

A

Na+ channels close; repolarization begins

19
Q

What happens when repolarization ends?

A

K+ channels close; hyperpolarization begins

20
Q

What is Absolute refractory period?

A

The time where a second action potential can not be initiated.

21
Q

What is Relative Refractory period?

A

Where a second action potential may rarely be initiated.

22
Q

When does the Absolute refractory period ends?

A

When the Na+ channels have gone back to normal within repolarization stage

23
Q

What is the All or none law?

A

The strength of the action potential is independent of the intensity of the stimulus.

24
Q

How do you code the intensity of the action potential?

A

By how many nuerons you fire/ rate of firing

25
Q

How are action potentials unitary?

A

Neurons can generate many action potentials, but it can not generate bigger of smaller action potentials.

26
Q

What is Saltatory Conduction?

A

Na+ enters at a previous node and sets up a currents that flows passively along the myelinated segment until the next node.

27
Q

What is the rate law?

A

Coding of intensity of a neuron and by the number of neurons firing.

28
Q

How are action potentials unitary?

A

Neurons can generate many action potentials, but it can not generate bigger of smaller action potentials.

29
Q

How can neurotransmitter be terminated? (3 ways)

A

Diffusion (passive), enzymatic degradation, reuptake

30
Q

What is required for the release of neurotransmitters?

A

Fusion of synaptic vesicles (requires Ca+)

31
Q

How do the transmitters molecules get to the other neuron?

A

They diffuse across synaptic cleft; bind to protein receptors in post synapse

32
Q

Transcranial Magnetic Stimulation?

A

It can be used to temporarily knock out/ enhance function in certain regions of the brain (thus can demonstrate causality).

33
Q

EEG

A

Has Low spatial resolution but high temporal resolution

34
Q

A patient thinks they either have a tumor, bone trauma, infraction, or hemmorhage. Which neuroimaging would be most likely use?

A

CT scan

35
Q

CT scan

A

Produces an image of the brain by shooting a beamo f x-rays from all angles to produce an image

36
Q

What is the first line of defense if you think someone is having a stroke

A

CT scan

37
Q

PET Scan

A

Iodine is injected into the bloodstream to image the blood vessels

38
Q

How can a DTI be useful?

A

It can be used to reconstruct white matter pathways.

39
Q

DTI

A

Looks the movement of water molecules

40
Q

EEG?

A

Brain waves; low spatial, high temporal; sleep studies, etc

41
Q

ERPs?

A

Stimulus is presented repeated and the recorded responses are averaged.

42
Q

Transcranial Magnetic Stimulation?

A

It can be used to temporarily knock out/ enhance
function in certain regions of the brain (thus can demonstrate
causality).

43
Q

DTI?

A

measures water diffusion along “highways”; reconstruct white matter pathways (tractography).

44
Q

Hydrophilic heads are on the___ while Hydrophobic tails on the _____

A

Outside; inside