Revision course nuc med Flashcards
SClerotic mets are which
Prostate
Some breast
carcinoid
medulloblastoma
colonic -some
lymphoma
lung
Lytic diseases
thyroid
rcc
melanoma
HCC
lung
GI m
If bone mets in prostate - what does that mena staging
8+
T3B+
Osteoid osteoma on nuc med
nidus will be hot
Cuases of super scan
Mets everywhere
metabolic - osteopetrosis, dystrophy, hyperparathyroidism
3 phase bone scan
3 diagnosis
Early pool
Blood pool
Bone pool
Infeciton hot on all
Aseptic loosening - only on bone
Soft tissue inflammation - NOT hot on bone.
indications for VQ
PE
Chronic Pulmonary Hypertension
Surgical planning
rules on order of nucs in VQ
if using technetium have to do the ventilation bit first.
causes of mismatch perfusion
PE
vasculitis
asthma
cause of a matched defect
consolidatoin
when to do a DMSA for UTI
after 6 weeks so scarring has gone
MAG3 looks at
tubular excretion
when to do a MAG3
consideration of hydronephrosis where no obstructing cause is seen
nuclear med cystogram for what
reflux.
HIDA
hot rim sign
cholecystitis
appearance of an absent GB due to upatek fo adjacent tissue
other causes of HIDA
absent gb sign
no gb, cholecystitis, gallstones
gastric dumping syndrome is what definition
70% gone in 3 mins
drawback of using white cell scan
have to stop abx for 2 weeks as can interfere with scan
Meckels scan
pertechnetate
Neuroendocrine/carcinoid/NET
Somatostatin receptor –> Octretide
MIBG Indin 124
FDG PET Fl18
relationship of Ki 67 mitotic index and expresison of neuroendocrine tumours
low ki67 - well differentiated.
lots of somatostain – god or octretide
FDG cold as slow growing.
high ki67, poorly differentiate and fast growing. FDG hot.
not good for octreatide.
MIBG will light up where normally
hot cheeks hot liver.
sympathetic adrenergic tissue
NO SPLEEN
parathyroid adneoma work up
US first
then if not found do SESTAMIBI scan at 20 min and 3 hours.
PTH adenoma will retain at 3 hours.
Thyroid nodule work up
Pertechnetate. or I123 for diagnosis
Iodine 131 for papillary thyroid cancer therapy
what does a DAT scan use
Iodine 123 Loflupnane will bind to the caudate end of the nerves from the substantia nigra
hummingbird sign
PSP
Nuc med for dementia
HMPAO or FDG
same patterns
F18 is made in a
cyclotron
Tc 99 is made in a
generator
indsications for a PET
mets
occult primary
biopsy target
recurrent tumour
when can you do a PET after different interventions?
1 week - biopsy
6 weeks - surgery
4 weeks - radiofrequency ablation
2-4 weeks - chemo
2-6 months - radiotherapy
what sizew lesion is occult on PET
<7mm
Lymphoma staging
1 - single group
2
3 - above the diaphragm
Types of NHL
diffuse B cell - look luike anything, mets
follicular - nodes everywhere
GIST are seen on
PET
80% positive