CORE Breast Flashcards

1
Q

when to use US

A

when a felt lump not seen on mammogram

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2
Q

MRi indications include

A

high risk patients
evaluation of diangosed diseased
chemo response
residual disease
recurrene

occult breast cancer with axillary mets
assessment of breast implants

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3
Q

what is the pathogenesis pathway of breast cancer

A

Normal

Flat epithelial atypia

atypical ductal hyperplasia

DCIS

IDC

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4
Q

what is upstaging

A

cancer i supstaged after excision

an increase from the core biospy

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5
Q

what does BRCA1 / BRCA2 mutation cause

A

increase lifetime risk of breast cancer

80% by 80

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6
Q

other risk factors for breast cancner

A

age, female

1st degree relative
prior chest radiatin
long term estrogen exposure

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7
Q

most common subtype of breast cancer is

A

IDC

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8
Q

IDC apperance

A

felt lump

irregular mass spiculated margins and ax pleomorphic clacifications

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9
Q

what are the other types of breast cancer

A

Tubular

Mucinous

Medullary

encapsulated papillary / solid papillary

adenoid cystic carcinoma

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10
Q

mucinous carcinom more common

A

in old women

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11
Q

Medullary carcinoma is found in

A

younger women with BRCA1 gene mutation

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12
Q

Appearanc3e of an encapuslated papillary carcinoma

A

discharge.
round oval mass.
circumscrbied margins.

US complex cystic solid mass.

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13
Q

inflammatroy carcinoma will appear as

A

skin distortion
edema

mammo - large, dense, trabecular thickening.

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14
Q

what is pagets disease of the nipple

A

DCIS that infiltrates the nipple epidermis

erythema of the nipple

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15
Q

non metastatic disease most important prognostic factor

A

axillary lymph nodes

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16
Q

when to do lymph node dissection vs sentinal biopsy

A

dissection is done if sentinel lymph node is positive

or not identified

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17
Q

is Er and Pr a good thing

A

Yes

longer survival

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18
Q

if have HER2 what can you give

A

trastuzamab - herceptin

Tk inhibitor like lapatinib

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19
Q

triple negative is

A

bad

common with BRCA1 mutation

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20
Q

What does BIRADS 0 mean

A

more imaging required

only used in screening

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21
Q

BIRADS 1

A

normal

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22
Q

BIRADS 2

A

definitely benign

vacsular, bening calc
simple breast csts, inflammatory lymph nodes

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23
Q

BIRADS 3

A

probably benign. Leave no stone untunred to diagnose this

therefore, not used in screening#

circumnscribed solid mass
focal asymmetry
single group punctate calcifications

24
Q

BRIADS 3 f/ u

A

6 , 12, 24 months

25
Q

BIRADS 4

A

suspicious

biopsy needed

4A-C

26
Q

BIRADS 5

A

highly likely cancer

27
Q

BIRADS 6

A

known cancer

28
Q

nipple should be in profile view….

A

in at least one view

29
Q

what type of breasts have increased risk of cancer

A

fibroglandular

30
Q

asymmetry vs mass

A

mass is two views
asymmetry is only 1 view

31
Q

margins lexicon

A

circumscribed
microlobulated
obscured
indistinct
sapiculated

32
Q

density lexicon

A

fat containing
low density
equal density
high density

33
Q

shape lexicon

A

round
oval
irregular

34
Q

inversion vs retration of nipple

A

inversion may be congenital and not necessarily a sign of malignancy

35
Q

causes of trabecular thickening

A

edema

radiation therapy

36
Q

popcorn calc

A

hyalinising fibroadenoma

37
Q

milk of calcium exists in

A

CYSTS

38
Q

ROUND CALC ISA

A

BENIGN

39
Q

RIM calc is from

A

calc on a sphere.

egg shell / lucent centred

fat necrosis or a cyst

40
Q

what to do with amorphous calc?

A

grouped, reginonal or segmental distribution are needing a biopsy as more concerniing

otherwise its a benig nfeature

41
Q

coarse heterogenous calc

A

biopsy as may be malignant

42
Q

pleomorphic has what apperaance

A

dot and dashes

43
Q

pleomorphic often seen in

A

DCIS or IDC

biopsy needed

44
Q

fine linear

A

highly concerning

birads 5.

filling of ducts

45
Q

differential for architectural distoriton

A

invasive malignancy
complex sclerosing lesions/radial scar
post-biospy scar
fibrocystic change like sclerosing adneitis.

46
Q

all palpable masses are given

A

US

47
Q

breast fat vs other fat

A

hypoechoic

lipoma, fat necrosis, lymph node hilum: there are hyperechoic

48
Q

small calc better seen on MRI or mammo

A

mammo

49
Q

breast MRI

which sequences are important

A

both breast at same time

pre and post contrast with kinetic acquisitions

50
Q

multicentric cancer results in

A

mastectomy

51
Q

MRI can be used for what kind of breast implants

A

silicone

saline implants are done by examinaton, mamo and US

52
Q

MRi

bunch of grapes on NME internal enhancement pattern

A

DCIS

53
Q

oil cyst vs lipoma

A

oil cyst has peripheral calc

54
Q

dark internal septations on MRi are specific for

A

fibroadenoma

55
Q
A