MSK Flashcards

1
Q

osteitis deformans is also called

A

Pagets

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2
Q

what is the pathology of Pagets?

A

Osteclastic activity.
abnromal and excessive new bone with vascularity

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3
Q

common sites for pagets to affect

A

Skull
spine
pelvis
femur

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4
Q

Pagets radiological appearance

A

Osteolysis
Cortical thickening
Loss of corticomedullary differentiation
Coarsening of trabeculae
Increased density
Bony expansion
Deformity

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5
Q

Osteoclstic activity causes what?

A

resoprtion of the bone

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6
Q

phases of pagets

A

Actuive phase
intermediate phase - osteblast and osteclast activity
late inactive - heavy sclerosis

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7
Q

pagets in the vertebra

A

picture frame
sclerosis all the way around

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8
Q

what area of sclerosis is specific to the pelvis in Pagets

A

Heavy sclerosis of the ileopectineal line

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9
Q

why is sclerosis of the ileopectineal line important

A

it allows for some distinction from amlignancy

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10
Q

imaging options in pagets

A

Scinitigraphy
- see burden
- also see active areas
- see a leading edge

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11
Q

When comparing pagets disease to possible sarcoma on MRI what aspect of the marrow signla is important

A

in Pagets marrow signal is preserved

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12
Q

complications of Pagets

A

osseous deformity
fracture
neoplastia (sarcoma)
soft tissue mass
osteomyelitis
gout
Extramedullary haematopoiesis
deg joint disease
Neural compression

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13
Q

osteomyelitis in pagets - what bug

A

increased incidence of salmonella

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14
Q

why gout in pagets

A

associated hypuricaemia

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15
Q

with hand lesions what are the questions to be asking one self

A

Bilateral
Birth / childhood
Symptomatic

Density
Affected area
subluxations
erosiions
FHx
normal variant

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16
Q

features of acro-osteolysis

A

destruction of the terminal phlaanges.
osteoporosis
hyphoscoliosis

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17
Q

Bizarre Parosteal Osteochondromatous Proliferation

A

heterotopic ossification arising from, but not disrupting, the cortical bone to which it is attached.

18
Q

driller wrist

how does it occurt

A

The intense vibrations are thought to lead to microfractures allowing synovial fluid to create cysts (Fig 1). In severe cases, where occupational exposure persists, carpal fragmentation can eventually occur.

19
Q

hyper parathyroidism changes in the hands

A

subperiosteal resorption

Also resorption of the distal clavicles and lamina dura of the teeth.

20
Q

what is madelungs deformity

A

dysplasia of the radius resulting in an exaggerated radial inclination, a short forearm, dorsal dislocation of the ulnar head and a V- shaped proximal carpal row

21
Q

Melorheostosis

A

thickneing and fibrosis of overlying skin
centred on a diaphysis

22
Q

Ollier’s disease

A

non-hereditary failure of cartilage ossification leading to the presence of multiple enchondromata.

ucencies are seen in the diaphyses of long bones.

23
Q

What are the endocrine and biochemcial causes of disc calcification?

A

acromegaly
alkaptuonuria
calcium pyrophosphate dihydrate crystal deposition
hyperparathyroidism
haemachromatosis

24
Q

Which sytstemic disease causes disc clacification?

A

Amyloidosis?

25
Q

Which conditions result in immobilisaiton or fusion of the spine?

A

Poliomyelitis
Ank spond
Juvenile chronic arthritis
Trauma

26
Q

What are the two locations for disc calcification?

A

nucleus polposus and annulus fibrosis

27
Q

Causes of nuc pulposis include?

A

Degen spondylosis
ank spnd
Juvenile chronic arthritis
DISH
Gout

28
Q

Alkaptonuria tria of

A

homogentisic aciduria
arthritis
ochronsis

29
Q

What is ochronosis?

A

MSK manifestations of alkatonuira.
large joint arthrosis.

30
Q

How does alkatonuria and ank spond differ on lumber xr

A

If no osteophytes and intervertebral ligaments are calcified then think of alkaptonuria

31
Q

what are the different types of juvenile idiopathic arthritis?

A

Systemic arthritis
Oligoarthritis
Polyarthritis
Enthesis related arthritis
Psoriatic arthritis

32
Q

which joint is most affected by JIA

A

knee

33
Q

Osteochondrosis - what is it

A

deranged growing skeleton
focal disturbanc of endochondral ossificaiton

paediatric AVN

34
Q

causes of avascular necrosis

A

PLATIC RAGS

pancreatitis, prengnancy
lupus
alcohol
steroids
trauma
idiopathic
caisson disease, collagen vascular
radiation, rheumatoid
amyloid arthropathy
gaucher disease
sickle cell disease

35
Q

causes categorised for avascular neocrosis

A

vascular interruption
glboal - systemic inflammatory
intraluminal emboli - local thomrubs
intrinsice
extrinisc

36
Q

types of osteonecrosis of the knee

A

primary

secondary

post athroscopic

37
Q

What is SONK / Ahlback

A

spontaenous osteonecrosis of the knee

now called a subchondral insufficiency fracture

38
Q

Secondary ON affects who

A

younger patients
co moribd

39
Q

location of scondary ON

A

can affect anywhere

40
Q

osteochondritis dissecans cause

A

still not known