Questions Flashcards
What pressures need proving in ARDs
partial pressure of arterial 02 / inspired 02 to be <200mmhg with no evidence of heart failure
what can ARDS mimic without knowing the PA 02 / Fi02 level
heart failure pulmonary oedema
PIOPED II study was for what condition?
PE
Low probability and negative PE do what
No need for anticoag or anything else
High probability and negatvie CTPA do what?
MR angiography or venous ultrasound
how do you differentiate between RBILD and DIP
RBILD is nodular, in the centrilobular region with upper lobe GGO
DIP is lower lobe and peripheral, sometimes cystic within GGO
what are the complications of bronchial artery embolization?
Can knock off branches to spine, oesophagus and develop chest pain
also operative complications
most common malignant oesophageal malignancy
SSC
Aseptic lymphocyte-dominated vasculitis associated lesion (ALVAL) from what
metal on metal implant
McCune-Albright syndrome - this almost always only affects girls and consists of a triad of
cafe-au-lait spots, precocious puberty (or other endocrine pathology), and polyostotic fibrous dysplasia. The cafe-au-lait pigmentation is often on the back and can commonly be seen to respect the midline.
Juxta-articular osteoporosis, marginal erosions, gradual reduction of the joint space
Phemester triad
triad in TB
This disease is more similar to osteopoikilosis than the other bony dysplasias. It is inherited in an autosomal dominant fashion, but can arise sporadically too. It causes striking longitudinal striations in the metaphyseal regions of the long bones but patients are generally asymptomatic and it is usually therefore an incidental finding. The appearance is said to resemble stalks of celery.
Osteopathia striata
This benign condition leads to multiple small oval bone islands forming around the skeleton. Purportedly, once the epiphyses have fused the number remains static. They can show mildly increased uptake on a nuclear medicine bone scan. Whereas a bone island may exist in isolation or near isolation, the finding of multiple such lesions suggests the diagnosis of osteopoikilosis.
Osteopoikilosis
Cirrhosis – the presence of the excess iron in the liver leads to unusual signal properties on an MRI scan. Iron is paramagnetic and causes spin dephasing. T2* and T2 sequences are particularly vulnerable to this effect but lower than expected signal will be seen on all sequences. Importantly the signal from the spleen and bone marrow should be normal. By contrast they will be involved in cases of transfusional siderosis.
Generalised osteoporosis
Hook like osteophytes on the radial aspect of the metacarpal heads – these are highly characteristic
Chondrocalcinosis, particularly affecting the knees
Insulin dependent diabetes
Congestive cardiomyopathy
Skin pigmentation
Haemachromatosis
This is a non-comminuted fracture at the base of the thumb metacarpal, which requires operative fixation due to the action of Abductor Pollicis Longus causing dorsolateral dislocation.
Bennet
This describes a comminuted fracture through the proximal thumb metacarpal.
Rolando
Women over the age of 55 is the typical demographic for SIFK but it does also occur in men. It is the adult equivalent to osteochondritis dessicans of the knee. Typically the medial condyle is affected and often there is an associated meniscal tear. On x-ray the appearances are of medial femoral condyle flattening with or without a subchondral radiolucent area. On MRI bone marrow oedema can be seen (high signal on STIR sequences).
sonk - Subchondral insufficiency fractures of the knee
Enlargement of the paranasal sinuses – 75%
Posterior vertebral scalloping – 30%
Widening of the terminal tufts
Heel pad thickness >25mm
Premature osteoarthritis
Enlargement and erosion of the sella
Hyperostosis of the inner table of the skull
acromegaly
the name given to the symptoms caused by compression of the tectal plate. These are highly testable and the main feature is paralysis of vertical gaze.
Parinaud syndrome is
NF1 get what in brina
optic glioma
plexiform neurofibromaas
CNS hamartomas
NF1 for skeletal
sphenoid bone dysplasia
tibia bowing
posterior vertebrla scalloping
NF1 eyes and skin
Lisch nodule
Cafe au lait
xillary freckling
NF2 get what
central
schwannomas
meningiomas
ependymomas
a very nasty condition which develops a few weeks or months after a patient has received Gadolinium in patients with acute or chronic renal failure, in particular post liver or kidney transplant patients (NB. hepatorenal syndrome). No particular therapy for it has been found to be effective. Dyspnoea has been described in association with
Nephrogenic systemic fibrosis
the ossicles, lateral semicircular canal (Known by some as the Clint Eastwood sign) and lateral epitympanic wall (i.e. scutum) are often involved.
Cholesteatoma
Serpiginous flow voids over the surface of the cord are the main described feature on MRI.
dural AVFs
caused by either a vertebral artery occlusion or PICA occlusion.
Lateral Medullary Syndrome (Wallenburg syndrome)
The anterior choroidal artery arises from the
internal carotid artery
MRI blood over time
hyper acute - T1 iso T2 bright
acute - dark dark
easrly subacute - T1 bright, T2 dark
late subacute - bright bright
chronic - dark dark
Bilateral caudate lobe atrophy is which neurodegenerative disease
Huntingdons
High T2 and FLAIR in the thalami is what neurodegenerative disease?
Wenickes
Abnormal signal in the putamen and lateral thalami
which neuro degenerative diseease
Wilson disease
Medial caudate nuclei and putamina high t2 /FLAIR
what neuro degen condition
CJD
What happens in Keans - Saye syndrome
what are the MRI changes
basal ganglia changes
Leigh syndrome affects who and where in the brain are the MRI changes
kids
putamina
which part of the substntia nigra are involved in Parkinson
pars compacta
(thinned or blurred)
In Picks disease, precuneus is….
spared
Lewi Body dementia can spare the
Hippocampi
Brown-Sequard syndrome
damage to the dorsal columns leads to ipsilateral loss of touch sensation
contralateral loss of pain and temperature sensation due to damage to the lateral spinothalamic tracts (contralateral since these ascend after having crossed). There is also ipsilateral motor function loss.
lateral medullary syndrome is also called
wallenberg syndrome
what is lateral medullary syndrome caused by
cause by vertebral artery occlusion or PICA occlusion
Browns tumours are a feature of which systemic disease
hyperparathyroidism
in MS, involvement of which anatomical location is highly specific to MS
especially when differentiating to small vessel ischaemic changes
middle cerebellar peduncle
Thalamic involvement when querying MS might instead point to which condition?
ADEM
which form of CJD is the most common
sporadic
(85%)
familial is only 10%
Variant CJD will look like what on MRI
thalamuc will have high signal hockey stick sign
Autoimmune encephalitis can be a result of which phenomenon
where does it affect
limbic system
paraneoplastic syndrome
post viral thyroiditis is called what
De Quervains thyroiditis
anatomy of the eye regions can be split into…
Globe
Extra conal
Conal
intraconal
Pathology affecting the eye globe
retinoblastoma
melanoma
haemorrhage detachement
IgG4 endophthalmitis
Which eye conditions can affect all the eye compartment s
Sarcoidosis
Pseudotumour
Lymphoproliferative lesion
what are the eye conal pathologies
Rhabdomyosarcoma
Thyroid eye disease
Intraconal pathology
optic nerve
haematoma / angioma
glomus tympanicum can cause what symptom
tinnitus
most common posterior fossa tumour in kids
medullobnlastoma
Features of a spinal cord infarction vs subacute combined degeneration
which is a V shpape
subacute dorsal columss only
infarction will be whole column, often length down 2 vertebral bodies.
Acute infarction on DWI are
bright
with low ADC map values (restrict)
Cavernoma classicaly appearance is
popcorn
bright lobulated centre and rim of hypointensity.
Cerebral amyloid angiopath can give rise to
micro-haemorrhages at GW junciton
Causes of opaque maxillary antrum
Malignant - carcinoma / lymphoma
inflammatory - sinusitis, allergies, mucocele
other - FD, Cysts, Wegeners,
traumatic -
arachnoiditis
thickened nerve roots
why ?
Nerve roots adhere to the aspect of the space.
infection secondary to surgery / meningitis / subarachnoid haemorrhage.
Limbic system is made up of
Olfactory
parahippocampal gyrus
Hippocampus
cingulate gyrus
subcallosal gyrus
amygdala
septum pallucidem
hypothalamus
anterior thalamic nuclei
mamillary bodies
Anti - onconeuroantibody
Breast
Anti-amphiphysin
yo
ri
Anti - onconeuroantibody
Lung
hum ri, amphysisi, zic4
anna3
pca2
antivgkc
vgcc
nachr
Anti - onconeuroantibody
thymoma
GAD
CV2/CRMP5
VGKC
AChR
Anti - onconeuroantibody
Hodgkin lymphoma
Tr
mGluR1
Anti - onconeuroantibody
Colon
none
Legg Calve Perthese disease
age
best radiograph view
4- 12
frog leg
Duration of symtpoms for JIA
6 weeks
Infantile haemangioendothelioma
age
ax symptoms
features on image
<6month
heart failure
low platelets
vascular lesion
calc within
age for hepatoblastoma
6m - 3y
imaging appearance for hepatoblastoma
rim nehancement
HCC age in children
> 5
imaging appearance of HCC in kids
central scar that can calcify
which ovarian tumour produces oestrogen and pregesterone
Leydig Sertoli
Yolk sac tumour size
normally large at presentation
Granulose cell tumours produce oestrogen
what symptoms does this causes
irregular or post menopausal bleeding
tuberous sclerosis tria
epilepsy
facial angiofibroma
mental retardation
Neuroblastoma vs Wilms tumour
Peak age
Sign on kidney
midline crossing
calc
IVC
Neuro
- 2 years, drooping lily sign, crosses midline, calc is stippled, encases IVC
Wilms
- 3 - 4, claw sign, doesn’t cross midline, calc is less common /curvilinear, displaces ivc
ring enhacning lesions
mnemonic
Dr MAGIC
Demyelinating
radiation necrosis
mets
abscess
glioma
infarction
contusion
pyloric stenosis, most specific sign
string sign
narrow track of barium passing through a long pyloric canal
fibromatosisi coli is what
fibrous thickening of the SCm muscle, often after a difficult birth
no acutal mass
hirschsprung biospy which type
suction biopsy below transition point
(Pivot shift)
- High signal on STIR to the lateral femoral condyle and posterolateral tibial plateau with an associated tear of the anterior cruciate ligament tear
(Clip injury) - injury and MRI signal to which bones
- High T2 signal to the anterior aspect of the lateral femoral condyle and lateral tibial plateau with an anterior cruciate ligament and medial collateral ligament tear
Neuroendocrine tumour
Blueberry muffin syndrome
Metastatic cutaneous deposits
Opsomoclonus
neuroendocinre tumour
rapid jerky eye.
Neuroendocrine tumour
Hutchinson syndrome
limping due to bony metastases
wilms vs neuroblastoma
invade or encase IVC
wilms invades
Glomus tumours are what
benign vascular tumours which arise in patients in their 40s and 50s.
tender blue/red nodule under the finger nail.
what is a subungual exostosis
bone outgrowth.
adolescent
cortical and medullary continuity.
ring and arc calc
enchondroma
Acute idiopathic scrotal wall oedema syndrome
age
what is it
under 10
skin hypersensitivity but get unilateral scrotal wall swelling
risk factors for NEC
Prem
low birth weight
heart disease
jirschsprungs
perinatal asphyxia
The patient will be youngish, with a temporal lobe lesion (in fact approximately a third are frontal lobe lesions), a history of epilepsy (often refractory) and the lesion is described as bubbly – here given as multiple cysts. The lack of oedema or enhancement is also typical.
DNET
Auto Rec PKD ax to what
hepatic fibrosis
pancreatic fibrosis
caroli disease
portal hypertension
neonatal septic arthritis
bug
group D strep
sinus mucocele vs tumours
what sign
peripheral enhacnemetn typical for mucocele
renal masses by age
neonate
vs
pre-school
neonate - MDK, mesoblastic nephroma, nephroblastomatosis
pre-school
- Multilocular cystic (boys)
wilms
lymphomaea
heart disease is worse in which heterotaxy?
right sided - 80% die by 1 year
which heterotaxy is horsehoe ax with
Right sided
First branchial cleft cyst located
periparotid region
A third branchial cleft cyst is situated at
the base of the sternocleidomastoid muscle.
appearance of a cystic hygroma
multi loculated
found in the posterior triangle
what is a bochdalek hernia
hernia in diaphragm
morgani hernia
small diaphragm hernia at the front
contain mesenteric fat only
fibrous dysplasia in the skull
Fibrous dysplasia can affect the skull. It is usually described as having a ground glass appearance with cortical expansion and a swell-defined sclerotic margin.
timeframe for bronchopyulmonay dysplasia in neonate
28 days of being ventilated
cysts in communication with each other
MDK vs hydronephris
MDK they do not communicate so this would be hydronephrosis
Renal masses by age
Neonate:
Multicystic dysplastic kidney (second most common neonatal renal mass)
Mesoblastic nephroma (most common SOLID neonatal renal mass)
Nephroblastomatosis (can be a precursor to Wilms tumour)
Renal masses by age
Pre-school:
Multilocular cystic nephroma (affects boys, slightly younger than Wilms)
Wilms tumour (most common SOLID mass of childhood)
Lymphoma (can affect teenagers and adults as well)
An 18-month-old presents with abdominal enlargement and respiratory difficulty. The serum AFP is noted to be negative and endothelial growth factor is normal. A CT scan demonstrates a very large multicystic hepatic mass with no evidence of calcification. There is no evidence of any calcification or haemorrhage within the mass.
Mesenchymal hamartoma
wilson disease is inherited in what pattern?
autosomal recessive
what neuro symptoms do wilsons patients get
dysarthria
tremor
lentiform nucleus copper deposition
why is liver MRI normal in Wilsons
fatty depsoition is blaance dout by the paramagnetic effeects of copper
Musculoskeletal manifestations of wilsons
Generalised osteoporosis, subarticular cysts, chondrocalcinosis and arthropathy which can mimic CPPD
Kasabach-Merritt sequence
platelet trapping in haemangioendothelioma
prior to a HIDA scan for biliary atresia what can be given that speeds up biliary excretion
phenobarbitol
A 7-month-old boy with uncontrollable crying and vomiting is brought to A and E by his parents. He subsequently undergoes a CT which shows a hyperdense mass with intense homogeneous enhancement. The mass is sitting in the trigone of the left lateral ventricle. It is large but smooth with a lobulated border and no evidence of invasion. There are small foci of calcification. The lateral ventricle is dilated. On MRI there is isointensity on T1 and hyperintensity on T2 relative to the white matter, with punctate foci of T2 hypointensity.
Choroid plexus papilloma
in children predominate in the 4th ventricle, show T1 hypointensity with foci of high T2 signal.
Ependyomoma
Galeazzi fracture
Dislocation at the distal radio-ulnar joint in association with a radial fracture
kissing ovaries sign
from endometriosis
On an MRI scan a T2 low signal plaque may be seen between/around them.
appearance of a chondroblastoma
long bones
lucent, lobulated lesion, thin sclerotic margin,
Ovarian germ cell tumours include
teratomas, yolk sac tumours, choriocarcinomas and mixed germ cell tumour
embryonal carcinoma and dysgerminomas
ovary mass
elevation of AFP levels although this would be more classically associated with a
yolk sac tumour
difference between dermoid and teratoma
a dermoid is composed only of dermal and epidermal elements (which are both ectodermal in origin), whereas teratomas also comprise mesodermal and endodermal elements.
what are the nenatal cardiac duct dependant lesions
Duct dependent lesions:
Hypoplastic left heart syndrome
Severe coarctation
Interrupted arch
Pulmonary atresia
Severe Ebsteins anomaly
TGA (if no VSD)
age for wilms / nephrobalstoma
preschool 4
Neuroblastoma secretes what
chatacholamines or VIP
which neuroblastoma stage does best
IV
Mutilocular cystic nephroma has what appearance
mass of cysts
thick fibrous capsule
Mesoblastic nephroma affects what age and appears
neonate
solid
Predisposing syndromes for Wilms
Beckwith-Wiedemann syndrome - macroglossia, hemihypertrophy, visceromegaly, omphalocoele
DRASH syndrome - progressive glomerulonephritis and male pseudohermaphroditism
WAGR syndrome - Wilms tumour, aniridia, GU abnormalities, mental retardation
Perlman syndrome - polyhydramnios, macrocephaly, visceromegaly
Golabi-Behmel syndrome - macrostomia, macroglossia, occular hypertelorism
Bronchial atresia can affect any segment but which is classical
apicoposterior segment of the left upper lobe is absolutely classical, as is the age of the patient.
leighs disease is what kind of disease
sporadic mitochondrial genetic disease
Kearns-Sayre syndrome is another mitochondrial disorder which is associated with WHAT IN THE BRAIN
Subcortical calcifications and basal ganglia siderotic deposits.
Birt-Hogg-Dube syndrome is a very rare condition which predisposes to WHCI HKIDNEY LESIONS
chromophobic RCCs
what are branchial cleft cysts and how are they numbered
abnormalities from embryology.
1 is deep
2 is at the mandible / ear lboe
3 and 4 are below and idfficult to distinguish betwene on imagagin. around hyoid
conotruncal anomaly is what
It is an anomaly of the vessels leading from the heart
ovary
small (<3 cm) thick walled, rounded, cystic structure with peripheral vascularity
corpus luteal cyst
how to investigate endometriosis
TV ultrasound
commonest location of ectoic pregnancy
Ampulla of Fallopian tube
What are some differentials for an endobronchial lesions
SCC
mets
carcinoid
hamartoma
TA is ax with what conditions
DiGeorge
CHARGE
VSD
Right sided arch
differentials for cavitating neoplastic culprits
bronchogenic carcinoma (SCC)
metastatic squamous cell carcinoma
adenocarcinoma (Colon + breast)
what is may-thurner syndrome
left leg selling and thrombosis.
right common iliac ARTERY crosses over the left common iliac vein - compression
The azygo-oesophageal recess is formed by the interface of the
right lung and the mediastinal reflection of the azygos vei
The anterior junctional line is formed by the meeting of the
parietal and visceral pleura anteromedially.
posterior junctional line is formed by the meeting of the
pleural surfaces of the upper lobes behind the oesophagus.
right paratracheal line is formed by
the right wall of the trachea against the right lung.
IPF and NSIP
architecture pattern
IPF - macrocystic honeycombing
NSIP - GGO
IPF and NSIp
location of disease
IPF - apicobasilar gradient
NSIP - peripheral
IPF and NSIP
bronchiectasis / nodules
IPF - traction bornchiectasis s
NSIP - no nodules
IPF and NSIP
smoking association
IPF. - there is an assocation
NSIP - no association
Lung nodule follow up should not be done what what nodules
Calcification – diffuse, central, laminated or popcorn patterns
Perifissural nodules
<5mm maximum diameter nodules
<80mm3 nodules
BTS nodule guidlines for follow up
sizes
<5mm
5-6mmm
> 6mm
solid nodule, no follow up, 12 months, 3 months
sub-solid nodule - no follow up if <5 but then (3 months, 12 months, 2 years, 4 years)
azygo-oesophageal recess is formed by the interface of the
right lung and the mediastinal reflection of the azygos vein
anterior junctional line is formed by the meeting of
the parietal and visceral pleura anteromedially
posterior junctional line is formed by
the meeting of the pleural surfaces of the upper lobes behind the oesophagus.
Specifically egg-shell calcification
Silicosis and coal workers pneumoconiosis
Sarcoidosis
Aneurysm
Distance to the renal arteries –
10mm used to be the absolute minimum landing zone distance required
Aneurysm
aceeptable neck
Angle of the neck – this is measured one of two ways in the literature. Consequently there are two different values for an acceptable angle. A purely straight aneurysm would have a neck angle of either 180o or 0o in each of the different measuring systems. Thus the acceptable neck cut-off values are 120o or 60o in each case.
aneurysm
Common iliac artery (CIA) length –
Ideally the CIA should be longer than 20mm to accommodate the stents used.
Halo sign also seen in
Hameorrhagic mets
bronchioalveolar carcinoma (min invasive adeno)
fungal
mycobaterial infeciton
Wegeners
hypersenstiivty pnuemopnititis
contraindications to GTN on cardiac CT
Systolic blood pressure <100 mmHg
Hypertrophic obstructive cardiomyopathy
Sildenafil usage within the previous 24-48 hours
Aortic stenosis
Profound anaemia
involveme nt of the upper lung zones
BREASTS
Beryllosis
Radiation
EG
Ank spond
Sarcoid
TB
Silicosis
Lower long zone involvement
BADAS
Bronchiectasis
Asp Pneumonia
Drugs and Desquamative interstitial pneumonia
Asbestosis
Scleroderma
Peripheral, associated with CREST/Sjogrens/RA, chemotherapy
NSIP
Patchy. Associated with connective tissue diseases, CF, methotrexate, post-transplant
COP
Smoking, young patients, no bronchiectasis or honeycombing
RBILD