Review III

Question 1

tyramine

Answer 1

inhibited by cocaine

needs NET to get into cell to cause its effect

increases NE release, bc displaces from vesicle

Question 2

low dose epinephrine

Answer 2

beta2 vasodilation

at high dose - alpha1 vasoconstriction with reflex bradycardia

Question 3

norepinephrine

Answer 3

no beta2

increased mean pressure and TPR
-reflex bradycardia

Question 4

epinephrine

Answer 4

alpha 2

Question 5

isoproterenol

Answer 5

beta-selective

Question 6

phenylephrine

Answer 6

alpha1 agonist

vasoconstriction with reflex bradycardia

Question 7

fendolopam

Answer 7

D1 agonist

Question 8

dobutmine

Answer 8

beta1 agonist

Question 9

cardiogenic shock

Answer 9

dobutamine - beta1 agonist

Question 10

dopamine

Answer 10

beta1 and D1 agonist

Question 11

nasal decongestant

Answer 11

phenylephrine - alpha1 agonist

Question 12

methoxamine

Answer 12

alpha1 agonist

-similar to phenylephrine

Question 13

albuterol

Answer 13

beta2 agonist

Question 14

salmeterol

Answer 14

beta2 agonist - long duration

Question 15

formoterol

Answer 15

beta2 agonist - long duration

Question 16

dexedrine

Answer 16

amphetamine

Question 17

amphetamine intoxication

Answer 17

weak bases, so acidify urine to excrete it

Question 18

ephedrine

Answer 18

beta agonist and increased NE release

Question 19

platelet aggregation

Answer 19

alpha2

Question 20

phentolamine

Answer 20

alpha antagonist
reversible

-vasodilation - reflex tachycardia

Question 21

phenoxybenzamine

Answer 21

alpha antagonist
irreversible
alpha1 > alpha2

-Tx for pheochromocytoma

Question 22

pheochromocytoma

Answer 22

phentolamine or phenoxybenzamine Tx

Question 23

prazosin

Answer 23

alpha1 antagonist

less reflex tachycardia

Question 24

tamulosin

Answer 24

alpha1A antagonist

Tx for BPH

Question 25

benign prostatic hypertrophy

Answer 25

tamulosin

Question 26

propanolol

Answer 26

beta antagonist | lipid soluble - may cause drowsiness

Question 27

stage fright

Answer 27

propanolol

Question 28

metoprolol

Answer 28

beta1 antagonist

Question 29

atenolol

Answer 29

beta1 antagonist

Question 30

labetalol

Answer 30

alpha1 and beta antagonist

Question 31

timolol

Answer 31

beta antagonist high potency

Question 32

nadolol

Answer 32

beta antagonist long duration

Question 33

esmolol

Answer 33

beta1 antagonist rapid onset

Question 34

Tx for pheochromocytoma

Answer 34

phenoxybenzamine and beta blocker

Question 35

reduce mortality in CHF

Answer 35

carvedilol beta and alpha1 antagonist

Question 36

reserpine

Answer 36

blocks NE blocks vesicular transporter

Question 37

guanethidine

Answer 37

displacement and release of NE | -blocks NE release

Question 38

bretylium

Answer 38

antiarrhythmic blocks NE release

Question 39

guanadrel

Answer 39

rapid onset, short duration, less side effects like guanethidine

Question 40

clonidine

Answer 40

alpha2 agonist | -sudden withdrawal - hypertensive crisis

Question 41

methyldopa

Answer 41

central alpha2 agonist -false neurotransmitter HTN in pregnant floozies

Question 42

HTN in pregnant floozies

Answer 42

methyldopa

Question 43

guanabenz

Answer 43

central alpha2 agonist