Review III Flashcards by Matt Stanton | Brainscape

Q

tyramine

A

inhibited by cocaine

needs NET to get into cell to cause its effect

increases NE release, bc displaces from vesicle

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Q

low dose epinephrine

A

beta2 vasodilation

at high dose - alpha1 vasoconstriction with reflex bradycardia

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Q

norepinephrine

A

no beta2

increased mean pressure and TPR
-reflex bradycardia

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Q

epinephrine

A

alpha 2

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Q

isoproterenol

A

beta-selective

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Q

phenylephrine

A

alpha1 agonist

vasoconstriction with reflex bradycardia

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Q

fendolopam

A

D1 agonist

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Q

dobutmine

A

beta1 agonist

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Q

cardiogenic shock

A

dobutamine - beta1 agonist

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Q

dopamine

A

beta1 and D1 agonist

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Q

nasal decongestant

A

phenylephrine - alpha1 agonist

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Q

methoxamine

A

alpha1 agonist

-similar to phenylephrine

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Q

albuterol

A

beta2 agonist

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Q

salmeterol

A

beta2 agonist - long duration

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Q

formoterol

A

beta2 agonist - long duration

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Q

dexedrine

A

amphetamine

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Q

amphetamine intoxication

A

weak bases, so acidify urine to excrete it

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Q

ephedrine

A

beta agonist and increased NE release

Q

platelet aggregation

A

alpha2

Q

phentolamine

A

alpha antagonist
reversible

-vasodilation - reflex tachycardia

Q

phenoxybenzamine

A

alpha antagonist
irreversible
alpha1 > alpha2

-Tx for pheochromocytoma

Q

pheochromocytoma

A

phentolamine or phenoxybenzamine Tx

Q

prazosin

A

alpha1 antagonist

less reflex tachycardia

Q

tamulosin

A

alpha1A antagonist

Tx for BPH

Q

benign prostatic hypertrophy

A

tamulosin

Q

propanolol

A

beta antagonist

lipid soluble - may cause drowsiness

Q

stage fright

A

propanolol

Q

metoprolol

A

beta1 antagonist

Q

atenolol

A

beta1 antagonist

Q

labetalol

A

alpha1 and beta antagonist

Q

timolol

A

beta antagonist

high potency

Q

nadolol

A

beta antagonist

long duration

Q

esmolol

A

beta1 antagonist

rapid onset

Q

Tx for pheochromocytoma

A

phenoxybenzamine and beta blocker

Q

reduce mortality in CHF

A

carvedilol

beta and alpha1 antagonist

Q

reserpine

A

blocks NE

blocks vesicular transporter

Q

guanethidine

A

displacement and release of NE

-blocks NE release

Q

bretylium

A

antiarrhythmic

blocks NE release

Q

guanadrel

A

rapid onset, short duration, less side effects

like guanethidine

Q

clonidine

A

alpha2 agonist

-sudden withdrawal - hypertensive crisis

Q

methyldopa

A

central alpha2 agonist
-false neurotransmitter

HTN in pregnant floozies

Q

HTN in pregnant floozies

A

methyldopa

Q

guanabenz

A

central alpha2 agonist