Review antibiotic coverage

Question 1

Aminopenicillin used for

Answer 1

Amoxicillin/Ampicillin HHELPSS kill Enterococci

H. influenzae
H pylori
E coli
Listeria
Proteus
Salmonella
Shigella

Question 2

1st generation cephalosporin coverage

Answer 2

gram (+) cocci plus PEcK

Proteus
E. coli
Klebsiella

Question 3

Pen G, V used for

Answer 3

gram (+)
gram (-) rods - mainly Neisseria
spirochetes

Question 4

2nd generation cephalosporin coverage

Answer 4

gram (+) cocci plus HEN PEcKs

Question 5

Piperacillin, ticarcillin coverage

Answer 5

Penicillin coverage + Pseudomonas

Question 6

Docloxacillin, nafcillin, oxacillin coverage

Answer 6

Penicillin coverage + Staph aureus

penicilinase resistant, narrow spectrum

Question 7

Amoxicillin/Ampicillin coverage

Answer 7

Extended-spectrum penicillin
H. influenzae
H pylori
E coli
Listeria
Proteus
Salmonella
Shigella

Aminopenicillins are penicillinase-sensitive

Question 8

3rd generation cephalosporin coverage

Answer 8

Gram (-)

Meningitis, Pyelonephritis, Gonorrhea, Pneumonia

Question 9

Ceftriaxone used for

Answer 9

meningitis
gonorrhea
disseminated Lyme disease

Question 10

3rd generation cephalosporin with Psedumonal coverage

Answer 10

Cetazidime

Question 11

Carbapenem coverage

Answer 11

Gram (+) cocci
Gram (-) rods
Anaerobes

Use after other antibiotics have failed

Question 12

4th generation cephalosporin coverage

Answer 12

Gram (-) plus pseudomonas and Gram (+)

Question 13

Monobactam coverage

Answer 13

Gram (-) rods only

Used in renal insufficiency (cannot tolerate aminoglycosides) and penicillin allergies

Question 14

Vancomycin coverage

Answer 14

Gram (+) only

Question 15

Aminoglycosides coverage

Answer 15

Severe gram (+) rod infection
No anaerobe coverage (require O2 for uptake)

Question 16

Chloramphenicol coverage

Answer 16

Meningitis (SHiN bugs)

Rocky mountain spotted fever

Question 17

Tetracycline coverage

Answer 17

Borrelia burgdoferi
M. pneumoniae
Rickettsia
Chlamydia

Intracellular

Question 18

Clindamycin coverage

Answer 18

anaerobe - above diaphragm

also against invasive GAS infection

Question 19

Linezolid coverage

Answer 19

used for
MRSA
VRE

Question 20

Macrolide coverage

Answer 20

Atypical pneumonia (mycoplasma, chlamydia, legionella)
Gram (+) cocci
Pertussis
STIs (chlamydia)

Question 21

Trimethoprim coverage

Answer 21

Combo with sulfonamides

UTIs
Shigella
Salmonella
Pneumocystis jirovecii

Question 22

Sulfonamide coverage

Answer 22

Gram(+)
Gram(-)
Nocardia
Chlamydia

Question 23

Fluoroquinolone coverage

Answer 23

Gram (-) rods (urinary and GI)
Pseudomonas
Neisseria and some other gram (+)

Question 24

Daptomycin used for

Answer 24

S. aureus, especially MRSA

gram (+): Endocarditis, VRE, bacteremia

Question 25

Metronidazole

Answer 25

GET GAP

Giardia
Entamoeba
Trichomonas
Gardnerella
Anaerobes
Pylori, H.