Autoantibodies Flashcards
1
Q
Rheumatoid arthritis
A
Anti IgG (Rheumatoid factor) Anti-citrullinated protein Ab (ACPA) (more spec)
2
Q
CREST scleroderma
A
Anti-centromere
3
Q
Diffuse scleroderma
A
Anti-Scl-70 (anti-DNA topoisomerase)
4
Q
Drug-induced lupus
A
Anti-histone (seen in 50% SLE)
5
Q
SLE
A
Anti-nuclear (ANA)
Anti-Smith (high spec, low sens)
Anti-dsDNA
6
Q
Lupus nephritis
A
Anti-dsDNA
7
Q
Polymyositis/dermatomyositis
A
Anti-Jo-1
8
Q
Sjogren
A
Anti-SSA (Ro)
Anti-SSB (La)
9
Q
MCTD
A
Anti-U1-RNP (ribonucleoprotein)
10
Q
Pemphigus vulgaris
A
Anti-desmoglein
11
Q
Myasthenia gravis
A
Anti-AchR
12
Q
Celiac
A
Anti-endomysial (anti-tissue transglutaminase)
Anti-gliadin
13
Q
Primary biliary cirrhosis
A
Anti-mitochondrial
14
Q
Autoimmune hepatitis
A
Anti-smooth muscle
15
Q
Type 1 DM
A
Anti-glutamate decarboxylase
