Immunological drugs Flashcards by DJ Reloj

Q

Alemtuzumab

A

CD52

used in CLL

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Q

Muromonab

A

(OKT3)
CD3

immunosuppression in transplants

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Q

Natalizumab

A

alpha4-integrin

MS, Crohn

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Q

Rituximab

A

CD20

B-cell non-Hodgkin
CLL
RA
ITP

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Q

Cyclosporine

A

Cyclophilin - calcineurin inhibitor

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Q

Trastuzumab

A

HER2/neu

Breast cancer

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Q

Adalimumab

A

Soluble TNF-a

IBD
RA
ankylosing spondylitis
psoriasis

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Q

Sirolimus

A

FKBP-12
mTOR inhibitor

transplant

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Q

Tacrolimus

A

FKBP - calcineurin inhibitor

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Q

Abciximab

A

IIb/IIIa inhibitor

antiplatelet agent for PCI patients

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Q

Daclizumab

A

IL-2R

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Q

Omalizumab

A

IgE

Allergic asthma

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Q

Infliximab

A

Soluble TNF-a

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Q

Basiliximab

A

IL-2R

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Q

Ranibizumab

A

VEGF

neovascular age-related macular degeration

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Q

Denosumab

A

RANKL

Osteoporosis
inhibits osteoclast maturation

Q

Palivizumab

A

RSV F protein

RSV prophylaxis

Q

Bevacizmab

A

VEGF

CRC
renal cell ca

Q

Eculizumab

A

C5

PNH

Q

Azathioprine

A

blocks nucleic acid synthesis
purine metabolism

lupus nephritis

Q

Gluocorticoids target

A

NF-kB

Q

Etanercept

A

decoy TNF-a receptor (intercepts TNF-a)