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0 Immuno / Micro > Numbers: IL, IFN, LT, CD, Complement > Flashcards

Numbers: IL, IFN, LT, CD, Complement Flashcards

1
Q

Major chemotactic factor for neutrophils

A

IL-8
LTE4
C5a

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2
Q

IL-6

A

Secreted by macrophages

Causes fever and stimulates acute phase reactions

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3
Q

HLA subtype associated with celiac

A

DQ2

DQ8

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4
Q

IL-10

A

Inhibitory/modulatory

Secreted by Th2, and regulatory T cells

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5
Q

Il-1

A

AKA osteoclast activating factor
Fever, inflammation
Causes endothelium to express adhesion molecules
Induces chemokine secretion to recruit WBCs

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6
Q

Complement proteins causing anaphylaxis

A

C3a, C4a, C5a

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7
Q

Decay-accelerating factor is AKA

A

CD55

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8
Q

B27 associated with

A

Psoriatic arthritis
Ankylosing spondylitis
IBD arthritis
Reactive arthritis (Reiter syndrome)

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9
Q

Receptor for EBV

A

CD21 on B cells

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10
Q

Expresses CD4, CD25

A

Regulatory T cells

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11
Q

CD16

A

NK cells, binds

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12
Q

Enhances activity of NK cells

A

IL-2
IL-12
IFN-a
IFN-B

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13
Q

HLA subtype associated with Rheumatoid Arthritis

A

DR4

4 walls in a rheum

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14
Q

Glycoproteins synthesized by virus-infected cells that prime nearby cells for defense

A

IFN-a

IFN-b

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15
Q

CD56

A

NK cells

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16
Q

Regulatory T cells identified by expression of

A

CD3 - all T cells
CD4 - all Th cells
CD25, FOXP3

17
Q

Antibody-dependent cell-mediated cytotoxicity involves binding of what

A

CD16 (NK) on Fc region of a bound Ig

18
Q

IL-12

A

Secreted by macrophages
Activates NKC
Th0–>Th1 differentiation

19
Q

Mediates septic shock

Causes cachexia in malignancy

A

TNF-a

20
Q

CD34

A

hematopoetic stem cells

21
Q

HLA subtype associated with Hashimoto’s

A

DR3

DR5

22
Q

Complement protein for opsonization

A

C3b

23
Q

CD14, CD40

MHCII, B7

A

Macrophages

24
Q

HLA subtype associated with Goodpasture syndrome

A

DR2

25
Q

Expresses CD4, CD40L

A

Th

26
Q

Langerhans histiocytes express what markers

A

CD1a

S-100

27
Q

HLA subtype associated with hemachromatosis

A

A3

28
Q

IFN-gamma

A

Secreted by NK cells and Th1 cells

Activates macrophages

29
Q

HLA subtype associated with DM type 1

A

DR3

DR4

30
Q

IL-4 vs IL-5

A

IL-4 stimulates IgE and IgG switching

IL-5 stimulates IgA switching and eosinophils

0 Immuno / Micro (16 decks)

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