DNA viruses

Question 1

Latent in dorsal root or trigeminal ganglia

Answer 1

VZV - commonly dorsal root

HSV-1 usually in trigeminal

Question 2

Owl eye inclusions

Answer 2

CMV

Question 3

Erythema infectiousum

Answer 3

parvovirus b19

fifth disease

Question 4

Can cause diarrhea, conjunctivitis, pneumonia/URI

Answer 4

adenovirus

Question 5

Temporal lobe encephalitis

Answer 5

HSV-1

Question 6

Latent in Mononuclear cells

Answer 6

CMV

Question 7

Common cause of infectious acute hemorrhagic cystitis in children

Answer 7

adenovirus

Question 8

HPV serotypes causing condylomata acuminata

Answer 8

6, 11

1, 2 cause common warts

Question 9

Neoplastic diseases associated with EBV

Answer 9

endemic Burkitt lymphoma
Nasopharyngeal carcinoma

Hodgkin
Diffuse large cell
Oral hairy leukoplakia
Lymphoproliferative disorders

Question 10

Flesh-colored purple with central umbilication

Answer 10

Molluscum contagiosum

poxvirus

Question 11

Disease associated with JCV? Family of JCV

Answer 11

progressive multifocal leukoencephalopathy

polyomavirus

Question 12

High fevers (+/- febrile seizure) ending, then rash

Answer 12

Describes Roseola - HHV-6

HHV-7 is Roseola-like

Question 13

Downey cells

Answer 13

Foamy-appearing basophilic cytoplasm

EBV

Question 14

HHV-8 associated with what neoplasm

Answer 14

Kaposi sarcoma (endothelial)

Question 15

Latent in B cells

Answer 15

EBV

Question 16

Intranuclear eosinophilic inclusions

Answer 16

Type A Cowdry bodies
Type 1 Cowdry inclusions

Seen HSV-1, HSV-2, VZV

Question 17

Polyomavirus targeting kidney of transplant patients

Answer 17

BK virus

Question 18

(+) monospot test

Answer 18

EBV

Question 19

milkmaid blisters

Answer 19

cowpox

Question 20

slapped cheek rash in children

Answer 20

parvovirus B19

“Fifth disease”

Question 21

Primary infection of VZV manifests as

Answer 21

chickenpox
pneumonia
encephalitis

Question 22

Partially doublestranded and circular

Answer 22

HBV

Question 23

Latent in sacral ganglia (S2, S3)

Answer 23

HSV-2

Question 24

Viral conjunctivitis

Answer 24

adenovirus

URI followed by conjunctivitis

Question 25

Ruptured spleen during contact sports

Answer 25

EBV mononucleosis

Question 26

Aplastic crises in sickle cell disease

Answer 26

parvovirus B19

Question 27

Detected by (+) agglutination of sheep or horse RBC

Answer 27

monospot test detects presence of heterophile antibodies to EBV which react to sheep/horse RBC

Question 28

Infects spindle cells coming from vascular and lymphatic endothelial tissue

Answer 28

HHV-8

Question 29

EBV infects B cells through what

Answer 29

CD21

Question 30

Heterophile-negative mono

Answer 30

CMV

Question 31

Multinucleated giant cells seen on vesicular fluid smear

Answer 31

(+) Tzanck smear

HSV-1, HSV-2, VZV

Question 32

Reverse transcriptase (not retrovirus)

Answer 32

HBV

Question 33

Aminopenicillin causing macupapular rash for strep throat-like lesions

Answer 33

EBV mononucleosis

Question 34

Retinitis, esophagitis

Answer 34

CMV

esophagitis especially in HIV with CD4

Question 35

Hydrops fetalis in utero due to RBC destruction

Answer 35

parvovirus b19