Review Flashcards
Two mechanisms for disintegrants
Porosity and swelling
The tablets are prepared using minimal compression to produce a soft tablet
It has a creamy base of specially flavoured and coloured mannitol
Chewable tablets
This type of tablet is useful when administering larger tablets to children
Chewable tablets
What are two ways to seal capsule
Sealed by a colour band of gelatin
Sealed through a welding process that fuses the capsule cap to the body
Locking
Mr S has formulate hard tablets
What could be the reason?
Starch kaolin and dextrose
Mannitol lactose sorbitol
Lactose and sucrose
Lactose and sucrose
What is the important of dissolution test
To see if it is going to dissolve when it is supposed to
To see 100% is released
The rate of release is uniform from batch to batch
The rate of release is the same as the release rate from those batches proven bioavailability and clinically effective
Which one is correct in terms of faster efficacy?
ODT>lozenges>buccal>sublingual
Lozenge>buccal>sublingual>ODT
sublingual> buccal>ODT>lozenge
ODT>sublingual>buccal>lozenge
ODT>sublingual>buccal>lozenge
What is the problem with underwet granules
Binding
Soft and fragile tablets
Name 2 differences between buccal and sublingual tablets
Into cheek vs under tongue
The speed sublingual is faster
Which one impact the taste?
Strach kaolin and dextrose
Mannitol lactose and sorbitol
Sucrose
Mannitol lactose & sorbitol
What is produced in effervescent tablets when it comes in contact with water?
What is its role?
CO2
Acts as disintegrator
How to avoid moisture in gelatin capsules?
Small desiccant material
What is the problem with over wet granules
Hard granules and difficult to form tablets
