Reversals/anticholinergic agents

Question 1

Atropine bolus dose

Answer 1

0. 4 mg

0. 01 mg/kg

Question 2

Atropine concentration

Answer 2

0.4 mg/ml

1 mg/ml

Question 3

Atropine onset

Answer 3

60-90 seconds

Question 4

Atropine considerations

Answer 4

+++ HR
+ CNS
- secretions

Question 5

Glycopyrrolate bolus dose

Answer 5

0. 2-0.4 mg

0. 01 mg/kg

Question 6

Glycopyrrolate concentration

Answer 6

0.1 mg/ml

Question 7

Glycopyrrolate onset

Answer 7

2-3 min

Question 8

Glycopyrrolate duration

Answer 8

120-240 minutes

Question 9

Glycopyrrolate considerations

Answer 9

++ HR
No CNS
– Secretions
Watch for anticholinergic side effects

Question 10

Glycopyrrolate class

Answer 10

Anticholinergic

Question 11

Atropine class

Answer 11

Anticholinergic

Question 12

Nestigmine class

Answer 12

Anticholinesterases

Question 13

Neostigmine dose

Answer 13

0.02-0.08 mg/kg

Question 14

Neostigmine max dose

Answer 14

5 mg

Question 15

Nestigmine concentration

Answer 15

1 mg/ml

Question 16

Neostigmine onset

Answer 16

7 min

Question 17

Neostigmine duration

Answer 17

55-75 min

Question 18

Neostigmine metabolism

Answer 18

50/50 liver/renal

Question 19

Usual neostigmine/glycopyrrolate dose

Answer 19

1 mg neostigmine/0.2 mg glycopyrrolate

Question 20

Edrophonium dose

Answer 20

0.5-1 mg/kg

Question 21

Edrophonium concentration

Answer 21

10 mg/ml

Question 22

Edrophonium onset

Answer 22

1-2 min

Question 23

Edrophonium duration

Answer 23

15-60 min

Question 24

Edrophonium metabolism

Answer 24

70 renal/ 30 hepatic

Question 25

Usual edrophonium/atropine ratio

Answer 25

1 mg edrophonium/0.4 mg atropine