Anti-emetics Flashcards

1
Q

Zofran dose

A

4-8 mg

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2
Q

Zofran onset

A

30 min

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3
Q

Zofran duration

A

3-6 hours

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4
Q

Zofran concentration

A

2 mg/ml

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5
Q

Zofran class

A

Serotonin blocker

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6
Q

Zofran neurotransmitter

A

Serotonin

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7
Q

Zofran considerations

A
  • first line treatment

- Granisetron and dolasetron

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8
Q

Decadron dose

A

4-10 mg

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9
Q

Decadron onset

A

15-30 min

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10
Q

Decadron duration

A

36-54 hours

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11
Q

Decadron concentration

A

4 mg/ml

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12
Q

Decadron class

A

Glucocorticoid

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13
Q

Decadron considerations

A
  • perineal itching

- immunosuppression

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14
Q

Scopolamine dose

A

1.5 mg

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15
Q

Scopolamine onset

A

1-2 min

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16
Q

Scopolamine duration

A

2-8 hours

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17
Q

Scopolamine concentration

A

1.5 mg/patch

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18
Q

Scopolamine class

A

Anticholinergic

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19
Q

Scopolamine neurotransmitter

A

Muscarinic blocker of Acetylcholine

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20
Q

Scopolamine considerations

A
Best effect if applied > 4 hours prior to induction
Watch for anticholinergic side effects
\+ HR
\+++ CNS
--- secretions
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21
Q

Droperidol dose

A

0.625-1.25 mg

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22
Q

Droperidol onset

A

30 min

23
Q

Droperidol duration

A

2.5 hours

24
Q

Droperidol concentration

A

2.5 mg/ml

25
Q

Droperidol class

A

Butyrophenones

26
Q

Droperidol neurotransmitter

A

Dopamine

27
Q

Droperidol considerations

A

Prolongs QT

- Ekg prior, don’t give if QT >.440

28
Q

Phenerygan dose

A

12.5-25 mg

29
Q

Phenergan onset

A

3-5 min

30
Q

Phenergan concentration

A

25 mg/ml

31
Q

Phenergan class

A

Antihistamine

32
Q

Phenergan neurotransmitter

A

H1/D2/alpha blocking

33
Q

Phenergan considerations

A

Sedation

34
Q

Reglan dose

A

10-20 mg

35
Q

Reglan onset

A

2-5 min

36
Q

Reglan duration

A

2-4 hours

37
Q

Reglan concentration

A

5 mg/ml

38
Q

Reglan class

A

Benzamides

39
Q

Reglan neurotransmitter

A

Muscarinic blocker of acetylcholine

40
Q

Reglan considerations

A

Increase gastric motility
CNS depression
Extrapyramidal side effects

41
Q

Aprepitent dose

A

115-150 mg over 20-30 min

42
Q

Aprepitent onset

A

10 min

43
Q

Aprepitent duration

A

9-12 hours

44
Q

Aprepitent concentration

A

115-150 mg/vial

45
Q

Aprepitent class

A

Neurokinin 1 antagonist

46
Q

Aprepitent neurotransmitter

A

Substance P

47
Q

Aprepitent considerations

A

Used for chemotherapy

48
Q

Benadryl dose

A

20-50 mg

49
Q

Benadryl onset

A

15 min

50
Q

Benadryl duration

A

3-6 hours

51
Q

Benadryl concentration

A

50 mg/ml

52
Q

Benadryl class

A

Antihistamine

53
Q

Benadryl neurotransmitter

A

H1, H2

54
Q

Benadryl considerations

A

Sedation

Treatment of antiphylaxis