Anti-emetics Flashcards
1
Q
Zofran dose
A
4-8 mg
2
Q
Zofran onset
A
30 min
3
Q
Zofran duration
A
3-6 hours
4
Q
Zofran concentration
A
2 mg/ml
5
Q
Zofran class
A
Serotonin blocker
6
Q
Zofran neurotransmitter
A
Serotonin
7
Q
Zofran considerations
A
- first line treatment
- Granisetron and dolasetron
8
Q
Decadron dose
A
4-10 mg
9
Q
Decadron onset
A
15-30 min
10
Q
Decadron duration
A
36-54 hours
11
Q
Decadron concentration
A
4 mg/ml
12
Q
Decadron class
A
Glucocorticoid
13
Q
Decadron considerations
A
- perineal itching
- immunosuppression
14
Q
Scopolamine dose
A
1.5 mg
15
Q
Scopolamine onset
A
1-2 min
16
Q
Scopolamine duration
A
2-8 hours
17
Q
Scopolamine concentration
A
1.5 mg/patch
18
Q
Scopolamine class
A
Anticholinergic
19
Q
Scopolamine neurotransmitter
A
Muscarinic blocker of Acetylcholine
20
Q
Scopolamine considerations
A
Best effect if applied > 4 hours prior to induction Watch for anticholinergic side effects \+ HR \+++ CNS --- secretions
21
Q
Droperidol dose
A
0.625-1.25 mg
22
Q
Droperidol onset
A
30 min
23
Q
Droperidol duration
A
2.5 hours
24
Q
Droperidol concentration
A
2.5 mg/ml
25
Droperidol class
Butyrophenones
26
Droperidol neurotransmitter
Dopamine
27
Droperidol considerations
Prolongs QT
| - Ekg prior, don't give if QT >.440
28
Phenerygan dose
12.5-25 mg
29
Phenergan onset
3-5 min
30
Phenergan concentration
25 mg/ml
31
Phenergan class
Antihistamine
32
Phenergan neurotransmitter
H1/D2/alpha blocking
33
Phenergan considerations
Sedation
34
Reglan dose
10-20 mg
35
Reglan onset
2-5 min
36
Reglan duration
2-4 hours
37
Reglan concentration
5 mg/ml
38
Reglan class
Benzamides
39
Reglan neurotransmitter
Muscarinic blocker of acetylcholine
40
Reglan considerations
Increase gastric motility
CNS depression
Extrapyramidal side effects
41
Aprepitent dose
115-150 mg over 20-30 min
42
Aprepitent onset
10 min
43
Aprepitent duration
9-12 hours
44
Aprepitent concentration
115-150 mg/vial
45
Aprepitent class
Neurokinin 1 antagonist
46
Aprepitent neurotransmitter
Substance P
47
Aprepitent considerations
Used for chemotherapy
48
Benadryl dose
20-50 mg
49
Benadryl onset
15 min
50
Benadryl duration
3-6 hours
51
Benadryl concentration
50 mg/ml
52
Benadryl class
Antihistamine
53
Benadryl neurotransmitter
H1, H2
54
Benadryl considerations
Sedation
| Treatment of antiphylaxis
