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Clínica Médica - Debs > Reumato > Flashcards

Reumato Flashcards

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1
Q

AR - manifestações oculares

A

Sjögren
Espiclerite
Esclerite
Escleromalácia perfurante

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2
Q

AR - acometimento pulmonar

A
  • pleurite/DP
  • nódulos reumatoides
  • fibrose intersticial difusa
  • BOOP
  • Sd. Caplan
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3
Q

Sd. Caplan

A

nódulos pulmonares reumatoides + pneumoconiose

mineiros de carvão, silicose, asbestose

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4
Q

AR - critérios diagnósticos

A

1 - envolvimento articular
2 - sorologia (FR, ACPA)
3 - reagentes de fase aguda
4 - duração sintomas (> 6sem)

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5
Q

Condições FR +

A 
AR
LES
Sjögren 
Sífilis 
Calazar
TB
Mononucleose
Sarcoidose 
Hep B e C
Vacinação 
Hemotransfusão
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6
Q

importância anti-CCP na AR

A

alta especificidade

prognóstico

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7
Q

Mau-prognóstico na AR

A 
1 - altos títulos de FR e anti-CCP
2 - acometimento extra-articular
3 - HLA-DRB1 +
4 - erosões ósseas precoces
5 - síndrome de Felty
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8
Q

Efeitos colaterais Metotrexate

A 
Estomatite
Intolerância gastrointestinal 
Hepatotoxicidade
Nefrotoxicidade
Pneumonite por hipersensibilidade 
Mielotoxicidade
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9
Q

Agentes anti-TNFa

A

infliximab
adalimumab
golimumab

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10
Q

efeitos adversos ag. anti-TNFa

A

infecções oportunistas

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11
Q

Neutralizador do CD20

A

Rituximab

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12
Q

sd. Reiter

A

uretrite
conjuntivite
artrite

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13
Q

Artr. Reativas características

A

oligoarticular
assimétrica
MMIIs
dactilite, sacroileíte, fasciíte plantar

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14
Q

etiologia artrite reativa

A

Infecção intestinal/genital (Salmonella, Shigella, Yersinia, Campylobacter, Chlamydia)

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15
Q

Síndrome CREST

A

forma cutânea localizada scdm / Calcionse / Raynaud / Esofagopatia / Esclerodermia / Telangiectasias

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16
Q

AC cutânea localizada esclerodermia

A

anticentrômero (80%)

17
Q

anticorpos esclerose sistêmica

A

anticentrômero / antitopoisomerase I / FAN (pontilhado salpicado) / anti RNA polimerase / anti-U3 RNP

18
Q

capilaroscopia CREST

A

tortuosidade e dilatação capilares

19
Q

capilaroscopia cutânea difusa

A

Áreas avasculares (drop-out)

20
Q

d-penicilamina - efeitos adversos

A

mielotoxicidade / sd. nefrótica / miastenia gravis

21
Q

tto farmacológico fen. Raynaud

A

Antag. Cálcio - Nifedipino, Anlodipino, Diltiazem; Nitroglicerina tópica; Hidralazina …

22
Q

superposições na DMTC

A

AR; LES; ES; polimiosite

23
Q

anticorpo DMCT

A

anti-RNP U1

Clínica Médica - Debs (11 decks)

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