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Clínica Médica - Debs > Hepato > Flashcards

Hepato Flashcards

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1
Q

Fenomenos autoimunes hep B

A

Poliartrite
Glomerulonefrite
Urticária e angioedema

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2
Q

Fenomenos autoimunes hep C

A

Crioglobulinemia

Líquen plano

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3
Q

Período incubação hep A

A

4 sem

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4
Q

Período incubação hep C

A

7 sem

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5
Q

Período incubação hep B e D

A

8 a 12 sem

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6
Q

Hepatites com lesão periportal

A

Virais

Colestase

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7
Q

Hepatites com lesão centrolobular

A

Alcoólica

Isquêmica

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8
Q

Hepatite que desenvolve colestase

A

A

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9
Q

Hepatite Alcoólica

A

Leucocitose neutrofílica (PMN)

Necrose centrolobular

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10
Q

Único DNA vírus

A

Hep B

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11
Q

Marcadores mais importantes hep B aguda

A

HBsAg e anti-HBc IgM

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12
Q

Mutação pré-core

A

Falha síntese HBeAg
+ cirrose, hep fulminante
HBsAg +, HBeAg -, trabsaminases elevadas
Solicitar DNA

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13
Q

Mutação por escape

A

HBsAg +, anti-HBs +

Resistente à atividade neutralizante do anti-HBs

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14
Q

Hep B crônica %

A

Adultos 1-5%
Crianças 20-30%
RN 90%

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15
Q

Tríade de Charcot

A

Dor HD
Febre com calafrio
Icterícia

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16
Q

Pêntade de Reynolds

A 
Dor HD
Febre com calafrios
Icterícia 
Hipotensão 
Alteração sensório
17
Q

Sinal de Courvoisier

A

Icterícia + vesícula palpável e indolor

Neoplasia

18
Q

Hemocromatose - mutações

A

C282Y

H63D

19
Q

Suspeita de hemocromatose

A 
6Hs
Hepatopatia 
Heart
Hiperglicemia 
Hipogonadismo
Hiperpigmentação cutânea 
HArtrite
20
Q

Diagnóstico hemocromatose

A
  • IST (Fe sério/ TIBC x100) >50 ou 60%
  • Ferritina
  • Testes genéticos
21
Q

Drogas Hep B crônica

A

Alfapeginterferon
Tenofovir
Entecavir

22
Q

Child

A 
BR
Encefalopatia
Ascite
Tap (INR)
Albumina
23
Q

Meld

A

Bilirrubinas
INR
Creatinina

24
Q

Precipitantes da encefalopatia hepática

A 
Hemorragia digestiva
Hipocalemia 
Alcalose metabólica 
Diuréticos (alça e tiazídico)
Hipovolemia
Hipoxia
Desidratação 
Infecção
25
Q

Fisiopatologia sd. Hepatorrenal

A

Vasodilatação esplâncnica -> vasoconstrição renal

26
Q

Tratamento sd Hepatorrenal

A

Albumina + Terlipressina

Transplante

Clínica Médica - Debs (11 decks)

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