Reticular System -Bales Flashcards

1
Q

What will result from damage to the dorsal raphe nucleus?

A

hyperactivity of cortex

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2
Q

What will result from damage to the Raphe magnus nucleus?

A

hypersensitivity to pain (hyperalgesia)

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3
Q

What is Ondine’s curse?

A

Brainstem lesion resulting in a loss of autonomic breathing but not voluntary breathing (loss of reticular input to the phrenic nuclei but not CST (voluntary) input)

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4
Q

What breathing pattern will you see with a lesion to the bilateral cortex?

A

cheyne-strokes breathing

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5
Q

What breathing pattern will you see with a lesion to the midbrain?

A

central neurogenic hyperventilation (loss of pneumotaxic center)

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6
Q

What breathing pattern will you see with a lesion to the pons?

A

apneustic breathing

deep inspiration–> hold –> normal exhalation

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7
Q

What breathing pattern will you see with a lesion to the upper medulla?

A

cluster breathing

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8
Q

What breathing pattern will you see with a lesion to the lower medulla?

A

ataxic breathing (not regulated)

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9
Q

What is normal breathing called?

A

eupnea

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10
Q

Where is the major source of NE to the cortex?

A

locus ceruleus

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11
Q

What are the rostral neurons of the RF (reticular activating system) responsible for?

What would a lesion to the rostral neurons of the RF cause?

A

arousal and attention functions

hypersomnia /coma

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12
Q

What are the caudal RF neurons responsible for?

what would a lesion to the caudal RF neurons cause?

A

vegetative and reflexive functions

insomnia

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13
Q

What is the major input of the reticular formation?

A

lateral zone

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14
Q

What is the major output of the reticular formation?

A

medial and raphe zones

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15
Q

What is the role of the preBotiznger complex?

A

generates rhythm

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16
Q

What is the function of the parabrachial and kolliker-fuse nuclei?

A

respond to lung receptors and are essential for normal breathing

17
Q

A lesion to what region will result in no breathing?

A

between the medulla and C3 spinal cord due to loss of the input to the phrenic nuclei