Restrictive Lung Disease (Exam IV) Flashcards
TLC is ________ % of normal in mild restrictive lung disease.
65 - 80%
TLC is ________ % of normal in moderate restrictive lung disease.
50 - 65 %
TLC is ________ % of normal in severe restrictive lung disease.
< 50 %
The two chest x-rays below would likely be indicative of what?
Pulmonary Edema
Bilateral symmetrical butterfly appearing opacities.
What occurs at the cellular level with pulmonary aspiration?
- Surfactant producing cells are destroyed
- Capillary endothelium is destroyed
Where is aspiration most often seen on a CXR?
Superior Segment of the RLL
How would acute respiratory failure be defined?
- Inability to provide O₂ and eliminate CO₂
- PaO₂ < 60 mmHg despite O₂ administration
- Uncompensated metabolic alkalosis w/ PaCO₂ > 50 mmHg
Differentiate acute vs chronic respiratory failure.
Acute: ↑ PaCO₂ and ↓ pH
Chronic: ↑ PaCO₂ and compensated pH (from renal HCO₃⁻)
How is ARDS classified?
By its PaO₂ / FiO₂ ratio
P/F Ratio
What would be classified as mild ARDS?
PaO₂ / FiO₂ = 201 - 300 mmHg
What would be classified as moderate ARDS?
PaO₂ / FiO₂ of 101 - 200 mmHg
What would be classified as severe ARDS?
PaO₂ / FiO₂ of ≤ 100 mmHg
How could ARDS be diagnosed via CXR?
Bilateral findings in at least 3 lung quadrants not explained by pleural effusion or atelectasis.
Why might neuromuscular blockers be useful for ARDs?
- Less ventilator barotrauma
- Less inflammatory mediators
Why might prone positioning be useful for ARDS?
- Recruits Alveoli
- Improves V/Q mismatch
What is Sarcoidosis?
Systemic granulomatous disorder primarily involving lymph nodes and the lungs
What signs and symptoms might initially be seen with sarcoidosis?
Usually no symptoms at time of presentation
What signs and symptoms might be seen later in sarcoidosis?
- Wheezing, dyspnea, cough
- Cor pulmonale
- Hypercalcemia
What places can sarcoidosis affect other than the lungs and lymph nodes?
- Ocular (uveitis)
- Myocardial (conduction problems)
- Laryngeal
How is sarcoidosis diagnosed?
- Mediastinoscopy
- ↑ACE activity