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MB1: Respiratory > Restrictive lung disease > Flashcards

Restrictive lung disease Flashcards

1
Q

what intrinsic factors may affect gas exchange in ILD

A

inflammation/scarring

impairment of A-a barrier

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2
Q

what extrinsic factors may affect gas exchange in ILD

A 
obesity
kyphoscoliosis 
MND
pleural thickening 
pleural effusion
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3
Q

ILD is indicated when DLCO is below…

A

80%

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4
Q

name 2 antifibrotic drugs

A

pirfenidone, nintedanib

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5
Q

what is CPAP

A

continuous positive airways pressure

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6
Q

what may cause ILD

A

hypersensitivity
IPF
Radiation
Drugs

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7
Q

hypersensitivity to thermophilic bacteria may cause

A

farmers lung

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8
Q

hypersensitivity to avian proteins may cause

A

bird fanciers lung

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9
Q

hypersensitivity to fungi exposure may cause

A

malt workers lung

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10
Q

treatment of acute sarcoid?

A

none, it is self limiting

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11
Q

4 things sarcoid may cause

A

erythema nodosum
uveitis
lymphadenopathy
hypercalcaemia

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12
Q

what is pneumoconiosis caused by?

A

exposure to dust particles such as coal or minerals

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13
Q

what markers would be raised in sarcoid?

A

calcium, inflammatory markers, angiotensin converting enzyme (not a diagnostic)

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14
Q

what would a tissue biopsy of sarcoid show

A

non-caeseating granuloma

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15
Q

3 immunosuppressants used in treating sarcoid

A

anti-TNF
methotrexate
azathioprine

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16
Q

what type of hypersensitivity is hypersensitivity pneumonitis

A

Type III

17
Q

what is the most common ILD

A

IPF

18
Q

what secondary causes may cause IPF

A

nitrofurantoin, amiodarone, methotrexate exposure
rheumatoid
asbestos exposure

19
Q

true/false - antifibrotic drugs reverse fibrosis

A

false

20
Q

symptoms of simple pneumoconiosis

A

none!

21
Q

what is caplans syndrome

A

rheumatoid pneumoconiosis (created nodules)

22
Q

define asbestosis

A

diffuse pulmonary fibrosis caused by heavy asbestos exposure. present in sputum and lung biopsy

MB1: Respiratory (15 decks)

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