Responsible Choice of Antimicrobials

Question 1

Describe antimicrobial stewardship

Answer 1

Antimicrobial Stewardship  Co-ordinated interventions designed to improve and measure the appropriate use of antimicrobials by promoting selection of the optimal antimicrobial drug regimen , dose, duration of therapy and route of administration.

Question 2

Describe three ways in which the risk of antimicrobial resistance can be reduced by vets

Answer 2

Work with clients to avoid need for antimicrobial use
Choose right drug for right bug
Avoid inappropriate use

Question 3

What kind of bacteria do Penicillin G and first generation cephalosporins work on?

Answer 3

Gram positive beta lactams

Question 4

What kind of bacteria do Eruthromycin and tylosin work on?

Answer 4

Gram posistive macrolides

Question 5

What kind of bacteria do Gentamicin and Dihyrostreptomycin work on?

Answer 5

Gram negative aminoglycosides

Question 6

What factor affect the decision between bacteriocidal and bacteriostatic drugs

Answer 6

Bactericidal often favored as more effective when host defenses impaired

Question 7

What are first line antibiotics and how do they differ from second line ones?

Answer 7

First line drugs are fist administred for diseases and are usually chosen due to their fewer side effects and high clinical effectiveness.
Second line drugs are used when first line show no effect for the disease or have side effects.

Question 8

Describe the minimum selection concentration

Answer 8

The minimum concentration of an antibiotic required to produce selective resistance. ( can be lower than therapeutic concentration so if TC not maintained bacteria can still become resistant)