respiratory tract Flashcards
drugs
B2-adrenergic agonists
short;
- terbutaline
- salbutamol
- fenterol
long;
- formoterol
- salmeterol
PDE inhibitor
theophylline
increase cAMP and cGMP > bronchodilation
anticholinergics
short; ipratropium
long; tiotropium
glucocorticosteroids
beclomethason
budesonide
fluticason
ciclesonide
prednisolon
prednison
transactivation
transpression
=
inducing anti-inflammatory
inhibiting pro-inflammatory
asthma, non-allergic rhinitis
montelukast
leukotrine inhibitor, blocking inflammation
anti Th2
mepolizumab, IL5
reslizumab, IL-5
benralizumab, IL5R
dupilumab, IL4
tezepelumab, TSLP
cromones
cromoglycate
nedocromil
mast cell stabilizer
asthma, allergic rhinitis
omaluzimab
anti-IgE
anti allergic
mast cell inhibition
omalizumab
cromoglicic acid
antihistamine
montelukast
asthma children
reliever; short acting B2-agonist
controller; low dose ICS, not higher than medium dose LABA
asthma adults
reliever; low dose ICS
controller; can go to high dose ICS-LABA
A2-adrenergic agonists
oxymethazoline
xylomethazoline
non-allergic rhinitis
antihistamines
chloorpheniramine
clemastine
cetrizine
loratidine
levocabastine
azelastine
allergic rhinitis
gefapixant
P2X3 antagonist
cough targets
centrally acting opioids
codeine
noscapine
dextromethorfan
peripherally acting opioids
dibunic acid
productive cough
emollientia
expectorantia
mucolytica; broomhexine, acetylcysteine
LAMA
tiotropium
aclidinium
glycopyrronium
umeclidinium
COPD
PDE inhibitor
roflumilast
COPD
azithromycin
broad-spectrum antibiotic
preventative
COPD
nintedanib
tyrosine kinase inhibitor
reduces inflammation
pulmonary fibrosis
pirfenidone
inhibitor of fibroblast activation
pulmonary fibrosis
