respiratory tract Flashcards

drugs

1
Q

B2-adrenergic agonists

A

short;
- terbutaline
- salbutamol
- fenterol

long;
- formoterol
- salmeterol

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2
Q

PDE inhibitor

A

theophylline
increase cAMP and cGMP > bronchodilation

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3
Q

anticholinergics

A

short; ipratropium
long; tiotropium

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4
Q

glucocorticosteroids

A

beclomethason
budesonide
fluticason
ciclesonide

prednisolon
prednison

transactivation
transpression
=
inducing anti-inflammatory
inhibiting pro-inflammatory

asthma, non-allergic rhinitis

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5
Q

montelukast

A

leukotrine inhibitor, blocking inflammation

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6
Q

anti Th2

A

mepolizumab, IL5
reslizumab, IL-5
benralizumab, IL5R
dupilumab, IL4
tezepelumab, TSLP

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7
Q

cromones

A

cromoglycate
nedocromil

mast cell stabilizer

asthma, allergic rhinitis

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8
Q

omaluzimab

A

anti-IgE
anti allergic

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9
Q

mast cell inhibition

A

omalizumab
cromoglicic acid
antihistamine
montelukast

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10
Q

asthma children

A

reliever; short acting B2-agonist
controller; low dose ICS, not higher than medium dose LABA

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11
Q

asthma adults

A

reliever; low dose ICS
controller; can go to high dose ICS-LABA

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12
Q

A2-adrenergic agonists

A

oxymethazoline
xylomethazoline

non-allergic rhinitis

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13
Q

antihistamines

A

chloorpheniramine
clemastine

cetrizine
loratidine
levocabastine
azelastine

allergic rhinitis

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14
Q

gefapixant

A

P2X3 antagonist
cough targets

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15
Q

centrally acting opioids

A

codeine
noscapine
dextromethorfan

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16
Q

peripherally acting opioids

A

dibunic acid

17
Q

productive cough

A

emollientia
expectorantia
mucolytica; broomhexine, acetylcysteine

18
Q

LAMA

A

tiotropium
aclidinium
glycopyrronium
umeclidinium

COPD

19
Q

PDE inhibitor

A

roflumilast

COPD

20
Q

azithromycin

A

broad-spectrum antibiotic
preventative

COPD

21
Q

nintedanib

A

tyrosine kinase inhibitor
reduces inflammation

pulmonary fibrosis

22
Q

pirfenidone

A

inhibitor of fibroblast activation

pulmonary fibrosis