respiratory tract Flashcards
drugs
B2-adrenergic agonists
short;
- terbutaline
- salbutamol
- fenterol
long;
- formoterol
- salmeterol
PDE inhibitor
theophylline
increase cAMP and cGMP > bronchodilation
anticholinergics
short; ipratropium
long; tiotropium
glucocorticosteroids
beclomethason
budesonide
fluticason
ciclesonide
prednisolon
prednison
transactivation
transpression
=
inducing anti-inflammatory
inhibiting pro-inflammatory
asthma, non-allergic rhinitis
montelukast
leukotrine inhibitor, blocking inflammation
anti Th2
mepolizumab, IL5
reslizumab, IL-5
benralizumab, IL5R
dupilumab, IL4
tezepelumab, TSLP
cromones
cromoglycate
nedocromil
mast cell stabilizer
asthma, allergic rhinitis
omaluzimab
anti-IgE
anti allergic
mast cell inhibition
omalizumab
cromoglicic acid
antihistamine
montelukast
asthma children
reliever; short acting B2-agonist
controller; low dose ICS, not higher than medium dose LABA
asthma adults
reliever; low dose ICS
controller; can go to high dose ICS-LABA
A2-adrenergic agonists
oxymethazoline
xylomethazoline
non-allergic rhinitis
antihistamines
chloorpheniramine
clemastine
cetrizine
loratidine
levocabastine
azelastine
allergic rhinitis
gefapixant
P2X3 antagonist
cough targets
centrally acting opioids
codeine
noscapine
dextromethorfan