Respiratory System - Anatomy/Patho Flashcards
What are the main structures of the upper respiratory tract (7)
Nasal cavity Nasopharynx Oropharynx Larygopharynx Epiglottis Thyroid cartilage Cricoid ring
Major structures of the lower respiratory system (5)
Trachea Carina Right main-stem bronchi Left main-stem bronchi Secondary bronchi
Main responsibility of the respiratory system
Oxygenating blood and removing carbon dioxide waste
How is oxygen and carbon dioxide exchanged at the alveoli
Process of diffusion across a diffusion gradient
What is diffusion
Diffusion is a passive process that consists of the transport from one area of high concentration to an area of low concentration.
What happens when thoracic volume increases
Diaphragm expands which causes a decrease in intrathoracic pressure allowing air to be inhaled into the lungs. (Boyles law)
Major muscles of the respiratory system (3)
Accessory muscles
Diaphragm
Intercostal muscles
Transversus thoracic
Which nerve innervates the diaphragm
Phrenic nerve
Where does the phrenic nerve originate
Originates at C3-C5
C 3,4,5 keeps us alive
What is Aerobic Metabolism
The process by which glucose is converted to energy (ATP) requiring oxygen and water
What is Hypercapnea
An excess retention of carbon dioxide in the blood
What is Tidal volume
What is the total Tidal Volume for an adult
Amount of air entering lungs with each normal breath
Volume - 500mL
What is Residual Volume and what is the total volume in an adult?
Amount of air remaining in the lungs after forced expiration
Volume - 1200mL
What is Inspiratory Reserve and what is the volume (mL)
Maximal amount of air that can inhaled in excess of normal quite respirations
3000mL
What is expiratory reserve and what is the volume (mL)
The maximal amount of air expired following a passive expiration.
1100mL
What is Vital Capacity and what is the volume in an adult
Maximal amount of air expired following a maximal inspiration
volume- 4600mL
what is total lung capacity and what is the volume in an adult
Total volume of air in the lungs after maximal inspiration
Volume- 5800mL
Oxyhemoglobin dissociation curve
- What causes an increased affinity
and - Which way does the curve shift with increased affinity
- Increase in pH, Decrease Pco2, Decreased temperature
2. Left
Oxyhemoglobin dissociation curve
- What causes decreased affinity
- Which way does the curve shift with decreased affinity?
- Decrease in pH (acidosis), High Pco2, increased temperature
- Right
- What is Paroxysmal nocturnal dyspnea
2. What patients does this affect the most
- A sudden acute type of dyspnea caused during sleep. During sleep, the body fluid is redistributed, leading to pulmonary edema causing the pt to wake up gasping for air.
- Patients with left sided CHF.
Primary control centers for breathing
Medulla and Pons
In relation to ventilation, what changes do the chemoreceptors detect?
Changes in CO2 level, Hydrogen ion and oxygen levels in the blood of CSF
Where are the central chemoreceptors located?
Medulla
Where are the peripheral chemoreceptors located
Carotid bodies
- What is hypercapnia and
2. what does it do to respirations
- Increase of CO2 levels in the blood
- Lowers pH and stimulates the respiratory center this causes an increase in rate and depth of respirations (hyperventilation)
Dalton’s Law
The total pressure exerted by the mixture of inert (non-reactive) gases is equal to the sum of the partial pressures of individual gases in a volume of air
Henry’s Law
the amount of a gas that dissolves in a liquid is directly proportional to the partial pressure of that gas.
Boyle’s Law
Boyle’s Law states that pressure and volume are inversely proportional to each other. As the pressure increases the volume decreases, and as the pressure decreases the volume increases
What is Atelectasis
Atelectasis, the collapse of part or all of a lung, is caused by a blockage of the air passages (bronchus or bronchioles) or by pressure on the lung.
ETCO2 Phases 1-4
- Inspiratory baseline
- Expiratory upstorke marking the beginning of exhalation
- Plateau phase represents ventilation. at the end of this phase, ETCO2 is determined
- Expiratory downstroke, marks end of exhalation
What is the Hering-breuer reflex?
Protective mechanism that terminates inhalation, preventing overexpansion of the lungs