Respiratory System Flashcards

1
Q

Functions of respiratory system:

A
Conducts air into & out of lungs
Exchanges gases between air & blood
Humidifies air
Warms air
Filters air
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2
Q

Alveoli:

A

Saclike structures surrounded by capillaries
site of exchange of oxygen and CO2
300 million in lung
Provides surface area where diffusion takes place

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3
Q

What are the two cell membranes that aid diffusion?

A

membrane of alveolar cells

membrane of cells of capillary wall

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4
Q

Visceral (pulmonary) pleura

A

outer surface of lungs

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5
Q

Parietal pleura

A

inner surface of thoracic cavity & diaphragm

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6
Q

Pleural fluid

A

lubricating fluid between 2 membranes

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7
Q

Intrapleural pressure

A

pressure in pleural cavity between 2 membranes; less than atmospheric pressure

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8
Q

Increase in volume of intrathoracic cavity

A

Increases lung volume
Decreases intrapulmonic pressure
Causes air to rush into lungs (inspiration)

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9
Q

Decrease in volume of intrathoracic cavity

A

Decreases lung volume
Increases intrapulmonic pressure
Causes air to rush out of lungs (expiration)

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10
Q

What do inspiratory muscles do?

A

increase intrathoracic cavity volume

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11
Q

Muscles that elevate ribs

A

external intercostals, scalenes, sternocleidomastoid, pectoralis minor

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12
Q

Diaphragm

A

Flattens as it contracts
Puts in motion pressure changes that cause inspiration
Contraction moves abdominal contents forward & downward

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13
Q

Expiration:

A

No muscular effort needed at rest

Passive recoil of diaphragm & other muscles decreases intrathoracic cavity volume

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14
Q

What muscles work during forced expiration to pull ribs downward?

A

Internal intercostals
Rectus abdominis
Internal oblique muscles of abdominal wall

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15
Q

Airflow equation

A

Airflow = P1 − P2/Resistance

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16
Q

What is P1-P2?

A

pressure difference between 2 areas

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17
Q

What can increase airflow?

A

Amplifying pressure difference between 2 areas

Decreasing resistance to airflow

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18
Q

What is biggest factor affecting airflow at rest?

A

Diameter of airway

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19
Q

What decreases resistance to airflow in exercise?

A

bronchodilation

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20
Q

Tidal volume

A

amount of air moved per breath

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21
Q

Pulmonary ventilation

A

anatomical dead space + alveolar ventilation

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22
Q

Volume of air moved per minute

A

VE = VT × f

23
Q

Residual volume:

A

air left in lungs after max. exhalation

24
Q

What are factors promoting diffusion?

A

Large surface area of alveoli
Thinness of respiratory membrane
Pressure differences of oxygen & carbon dioxide between air in alveoli & blood
Partial pressure

25
Partial pressure
portion of pressure due to a particular gas in a mixture of gases
26
PO2 at sea level
159.1 mm Hg
27
PO2 in alveoli
105 mm Hg
28
PO2 in arterial blood entering lungs
40 mm Hg
29
PO2 in blood leaving lungs
100 mm Hg
30
PO2 in tissues
40 mm Hg
31
What provides the driving force for diffusion of oxygen?
differences between PO2 in alveoli & blood (65 mm Hg) and between blood & tissue (60 mm Hg)
32
PCO2 in atmospheric air
0.2 mm Hg
33
PCO2 in alveoli
40 mm Hg
34
PCO2 in arterial blood entering lungs
46 mm Hg
35
PCO2 in blood leaving lungs
40 mm Hg
36
PCO2 in tissues
46 mm Hg
37
Oxyhemoglobin
oxygen bound to hemoglobin
38
Deoxyhemoglobin
hemoglobin not bound to oxygen
39
How does an increase in temperature affect oxyhemoglobin disassociation?
Decreases affinity of hemoglobin for oxygen
40
How to pH effect oxyhemoglobin disassociation?
increase in acidity: decreases affinity | decrease in acidity: increase in affinity
41
How is carbon dioxide transported in body?
7% to 10% is dissolved in plasma 20% is bound to hemoglobin 70% is transported as bicarbonate
42
Oxygen capacity for females
14*1.34=18.8 volume %
43
Oxygen capacity for males
16*1.34=21.4Volume %
44
Repiratory control center
Portion of medulla oblongata & pons | Serves as pacemaker, generating a rhythmical breathing pattern
45
te & depth of breathing can be modified by
Higher brain centers Chemoreceptors in medulla Other peripheral inputs
46
Central Chemoreceptors
Located in medulla, separate from respiratory control center | Respond to changes within CSF, esp. in H+ concentration or
47
Peripheral Chemoreceptors
Located in carotid arteries & aortic arch | Respond to changes in blood PCO2 & H+ concentration
48
Other Neural Input
Stretch receptors in lungs & respiratory muscles | Proprioceptors & chemoreceptors in skeletal muscle & joints
49
Ventilatory equivalent of oxygen
ratio of pulmonary ventilation (VE) to oxygen (VO2): VE/VO2
50
Ventilatory equivalent of carbon dioxide
ratio of pulmonary ventilation (VE) to carbon dioxide (VCO2): VE/VCO2
51
Light-intensity:
less than VT
52
Moderate-intensity
between VT and RCP
53
High-intensity
>RCP