Respiratory Physiology Flashcards
volume can be inspired over and above the tidal volume
inspiratory reserve volume
volume inspired or expired with each normal breath
tidal volume
volume that can be expired after the expiration of a tidal volume
expiratory reserve volume
volume that remains in the lungs after a maximal expiration
residual volume
which of the lung volumes and capacities cannot be measured by spirometry?
residual volume
total lung capacity
sum of tidal volume and inspiratory reserve volume
inspiratory capacity
sum of expiratory reserve volume and residual volume
functional residual capacity
volume of air that can be forcibly expired after a maximal inspiration
vital capacity
Determination of residual volume
functional residual capacity - expiratory reserve volume
equilibrium/resting volume of lung
functional residual capacity
FEV1/FVC: obstructive lung disease
decreased
FEV1/FVC: restrictive lung disease
normal or increased
Gas exchange: N2O
perfusion-limited exchange
Gas exchange: oxygen - normal conditions
perfusion-limited exchange
Gas exchange: CO
diffusion-limited exchange
Gas exchange: oxygen - strenuous exchange
diffusion-limited exchange
Gas exchange: CO2
perfusion-limited exchange
Gas exchange: CO2
perfusion-limited exchange
Where is perfusion highest/lowest?
Perfusion is lowest at apex (zone 1)
Perfusion is highest at base (zone 3)
Where is ventillation highest?
Base
Where is V/Q ratio highest/lowest?
V/Q ratio is highest at apex
V/Q ratio is lowest at base
Zone 1
alveolar>arterial>venous
Zone 2
arterial>alveolar>venous
Zone 3
arterial>venous>alveolar
What is the response of the lungs to hypoxia?
Hypoxic vasoconstriction
Medullary response center
reticular formation
Medullary response center: inspiratory center, basic rhythm
dorsal respiratory group
Medullary response center: expiration, overdrive mechanism during exercise, forced inspiration and expiration
ventral respiratory group
Apneustic center
lower pons
Pneumotaxic center
upper pons
Which pontine center stimulates/inhibits inspiration?
stimulates inspiration-apneustic center
inhibits inspiration-pneumotaxic center
Majority of bronchial circulation returns to right atrium or left atrium?
right atrium - 1/3
left atrium - 2/3
normal inspiration is active or passive?
active
normal expiration is active or passive?
passive
What muscles are involved in quiet breathing?
only the diaphragm
Emphysema:
compliance
elasticity
compliance increased
elasticity decreased
Fibrosis:
compliance
elasticity
compliance decreased
elasticity increased
active component of surfactant
dipalmitoylphosphatidylcholine/lecitin
lung zone 1: alveolar capillary pressure vs alveolar air pressue
lung zone 1: alveolar capillary pressure IS LESS THAN alveolar air pressue
lung zone 2: alveolar capillary pressure vs alveolar air pressue
lung zone 2: alveolar capillary pressure IS GREATER THAN alveolar air pressue DURING SYSTOLE
lung zone 3: alveolar capillary pressure vs alveolar air pressue
lung zone 3: alveolar capillary pressure IS GREATER THAN alveolar air pressue