Endocrine Physiology Flashcards

1
Q

signal transduction system: ADH V1 receptor

A

IP3/DAG

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2
Q

signal transduction system: ADH V2 receptor

A

cAMP

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3
Q

signal transduction system: angiotensin II - vascular smooth muscles

A

IP3/DAG

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4
Q

signal transduction system: angiotensin II - epithelial cells

A

cAMP

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5
Q

signal transduction system: cathecolamine A1 receptors

A

IP3/DAG

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6
Q

signal transduction system: cathecolamine B1 and B2 receptors

A

cAMP

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7
Q

basophilic pituitary cells

A

FSH, LH, ACTH, TSH, MSH

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8
Q

acidophilic pituitary cells

A

GH, prolactin

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9
Q

diabetogenic hormones

A

cortisol, GH, glucagon, epinephrine

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10
Q

Accumulating substrate: 21-beta-hydroxylase

A

17-hydroxyprogesterone

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11
Q

Accumulating substrate: 11-beta-hydroxylase

A

11-deoxycortisone

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12
Q

Accumulating substrate: 17-alpha-hydroxylase

A

pregnenolone

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13
Q

signal transduction system: insulin

A

tyrosine kinase

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14
Q

signal transduction system: glucagon

A

cAMP

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15
Q

which diabetes mellitus type is autoimmune?

A

Ia

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16
Q

Bone component for compressional strength

A

bone salts

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17
Q

Bone component for tensile strength

A

organic matrix

18
Q

PTH is stimulated by hypomagnesemia except

A

hypomagnesemia caused by alcoholism

19
Q

PTH causes increased or decreased phosphate reabsorption?

A

decreased phosphate reabsoprtion

20
Q

PTH causes increased or decreased urinary calcium?

A

increased calcium reabsorption

21
Q

Vitamin D causes increased or decreased phosphate reabsorption?

A

increased phosphate reabsoprtion

22
Q

Vitamin D causes increased or decreased serum phosphate?

A

decreased serum phosphate

23
Q

PTH causes increased or decreased serum phosphate?

A

decreased serum phosphate

24
Q

Vitamin D causes increased or decreased serum phosphate?

A

increased serum phosphate

25
Q

what is effect of ethanol on ADH?

A

decrease

26
Q

thyroid levels in hepatic failure

A

decrease in TBG
decrease in total thyroid hormone levels
normal levels of free hormone

27
Q

thyroid levels in pregnancy

A

increase in TBG
increase in total thyroid hormone levesl
normal levels of free hormone

28
Q

CRH-containing neurons are located in

A

paraventricular nuclei

29
Q

high-dose dexamethasone is not suppressed by what tumor: ACTH-secreting tumors or adrenal cortical tumors?

A

ACTH-secreting tumor

30
Q

aldosterone secretion is increased by hypokalemia or hyperkalemia?

A

hyperkalemia

31
Q

in Cushing’s syndrome, ACTH is increased or decreased?

A

decreased

32
Q

in Conn’s syndrome, potassium is increased or decreased?

A

decreased

33
Q

what is the effect of glucagon on urea production?

A

glucagon increases urea production

34
Q

pancreatic receptor (beta cells) for glucose

A

GLUT-2

35
Q

what is the effect of acetylcholine on insulin and glucagon?

A

acetylcholine increases both insulin and glucagon

36
Q

high aldosterone is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency

A

high aldosterone is seen in 17-alpha-hydroxylase deficiency

37
Q

low androgen is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency

A

low androgen is seen in 17-alpha-hydroxylase deficiency

38
Q

hypotension is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency

A

hypotension is seen in 21-beta-hydroxylase deficiency

39
Q

1-alpha-hydroxylase is stimulated by high or low phosphate?

A

low phosphate

40
Q

true or false: PTH increases calcium absorption in GIT

A

false