Endocrine Physiology Flashcards
signal transduction system: ADH V1 receptor
IP3/DAG
signal transduction system: ADH V2 receptor
cAMP
signal transduction system: angiotensin II - vascular smooth muscles
IP3/DAG
signal transduction system: angiotensin II - epithelial cells
cAMP
signal transduction system: cathecolamine A1 receptors
IP3/DAG
signal transduction system: cathecolamine B1 and B2 receptors
cAMP
basophilic pituitary cells
FSH, LH, ACTH, TSH, MSH
acidophilic pituitary cells
GH, prolactin
diabetogenic hormones
cortisol, GH, glucagon, epinephrine
Accumulating substrate: 21-beta-hydroxylase
17-hydroxyprogesterone
Accumulating substrate: 11-beta-hydroxylase
11-deoxycortisone
Accumulating substrate: 17-alpha-hydroxylase
pregnenolone
signal transduction system: insulin
tyrosine kinase
signal transduction system: glucagon
cAMP
which diabetes mellitus type is autoimmune?
Ia
Bone component for compressional strength
bone salts
Bone component for tensile strength
organic matrix
PTH is stimulated by hypomagnesemia except
hypomagnesemia caused by alcoholism
PTH causes increased or decreased phosphate reabsorption?
decreased phosphate reabsoprtion
PTH causes increased or decreased urinary calcium?
increased calcium reabsorption
Vitamin D causes increased or decreased phosphate reabsorption?
increased phosphate reabsoprtion
Vitamin D causes increased or decreased serum phosphate?
decreased serum phosphate
PTH causes increased or decreased serum phosphate?
decreased serum phosphate
Vitamin D causes increased or decreased serum phosphate?
increased serum phosphate
what is effect of ethanol on ADH?
decrease
thyroid levels in hepatic failure
decrease in TBG
decrease in total thyroid hormone levels
normal levels of free hormone
thyroid levels in pregnancy
increase in TBG
increase in total thyroid hormone levesl
normal levels of free hormone
CRH-containing neurons are located in
paraventricular nuclei
high-dose dexamethasone is not suppressed by what tumor: ACTH-secreting tumors or adrenal cortical tumors?
ACTH-secreting tumor
aldosterone secretion is increased by hypokalemia or hyperkalemia?
hyperkalemia
in Cushing’s syndrome, ACTH is increased or decreased?
decreased
in Conn’s syndrome, potassium is increased or decreased?
decreased
what is the effect of glucagon on urea production?
glucagon increases urea production
pancreatic receptor (beta cells) for glucose
GLUT-2
what is the effect of acetylcholine on insulin and glucagon?
acetylcholine increases both insulin and glucagon
high aldosterone is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency
high aldosterone is seen in 17-alpha-hydroxylase deficiency
low androgen is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency
low androgen is seen in 17-alpha-hydroxylase deficiency
hypotension is seen in:
A. 21-beta-hydroxylase deficiency
B. 11-beta-hydroxylase deficiency
C. 17-alpha-hydroxylase deficiency
hypotension is seen in 21-beta-hydroxylase deficiency
1-alpha-hydroxylase is stimulated by high or low phosphate?
low phosphate
true or false: PTH increases calcium absorption in GIT
false