Respiratory Failure Flashcards
Define hypoxemia:
failure of oxygenation
What is the Pa02 value associated with type I respiratory failure?
Pa02< 60 mmHg
Define type I respiratory failure:
processes impair oxygen transfer in the lung causing hypoxemia
What factors lead to hypoxemia?
low pressure of inspired air impaired diffusion V/Q mismatch shunt hypoventilation
Impaired diffusion is primarily a result of:
increased thickness of alveolar membrane due to pulmonary fibrosis
How would exercise or increased CO effect diffusion?
Increased flow of blood through capillary beds means less time available for gas exchange to occur
What is normal V/Q ratio?
~0.8
What happens to blood flow with the presence of a shunt?
either the alveolar capillary membrane or the lungs are bypassed due to cardiac defect (patent foramen ovale).
Hypoventilation leads to depression in _____ and overall leads to hypercapnia.
central respiratory centers
Define type II respiratory failure:
inadequate ventilation leads to C02 retention with hypercarbia
What is the PaC02 value associated with type II respiratory failure?
PaC02 > 55mmHg
What factors lead to failure of ventilation?
central hypoventilation neuromuscular weakness airway obstruction chest wall deformities marked abdominal interference with diaphragm descent
How should your body respond if you are hypercapnic?
ventilation increases as PC02 rises (eliminate excess C02)
What are the indications or mechanical ventilation?
elevated cost of breathing
inadequate oxygenation or ventilation
retention of pulmonary secretions
airway protection
Can a V/Q mismatch lead to a shunt?
yes.
Respiratory _____ is associated with hypercapnia.
acidemia
Which type(s) of respiratory failure are associated with gas exchange impairment?
Type I
Which type(s) of respiratory failure are associated with ventilatory pump impairment?
Type II