Respiratory Conditions Flashcards
Aetiology COPD
Smoking
alpha-1 trypsin deficiency
Pathology COPD
Chronic inflammatory condition causing progressive airflow obstruction
Symptoms COPD
SOB, Cough, sputum, wheeze
Little diurnal variation
Weight loss, peripheral oedema
Investigations COPD
CXR, FBC, BMI, ECG
Spirometry - FEV1 <80%, FEV1/FVC <0.7
CO transfer
ABG
Signs COPD
Cyanosis, CO2 flap, decreased breathing sounds
Treatment COPD
Avoid RFs
SABA, LABA
Inhaled glucocorticoids
Long term oxygen - if paO2 less than 7.3/oedema
Types of obstructive airway diseases
Chronic bronchitis
Emphysema
Asthma
COPD
What is cor pulmonale
Pulmonary HT causing hypertrophy of LV and RHF
Types of restrictive lung diseases
Sarcoidosis
Idiopathic pulmonary fibrosis
Pleural causes of restrictive lung disease
Pleural effusions (fluid between visceral and parietal pleura) Pneumothorax (accumulation of air in pleura) Pleural thickening (scarring)
Presentation of restrictive lung diseases
Abnormal chest x-ray
SOB
Respiratory and heart failure
Normal FEV1/FVC ratio
RFs for asthma
Genetic
Occupation (paints, solder, animals, grains)
Smoking
Gender
Pathophysiology of asthma
Chronic reversible inflammation of airways caused by increased sensitivity leading to airway obstruction (variable)
Symptoms of asthma
Wheeze, SOB, Chest tightness, dry cough (nocturnal)
Signs of asthma
Tachypnoea, tachycardia, cyanosis, wheeze
Investigations of asthma
FBC, U+E, spirometry, PEFR, trial of treatment
Treatment of asthma
SABA, LABA, ICS, steroid tablet
Treatment of acute asthma
Oxygen, steroids, nebulisers
Aetiology of Lung Cancer
Smoking, asbestos, radon, occupational exposure, pollution, pulmonary fibrosis
Symptoms of lung cancer
Haemoptysis, recurrent infection, cough, SOB, pain weight loss, lump, chest pain, hoarseness
Signs of lung cancer
Clubbing, lymphadenopathy, Stridor, collapsed lung, reduced expansion, reduced percussion, reduced breath sounds
Local effects of lung cancer
Pleural effusion Collapse Pneumonia Infection Abscess Bronchiectasis SVC syndrome
Investigations of lung cancer
CXR, bronchoscopy, biopsy, CT, PFTs, PET, sputum cytology,