respiratory anatomy Flashcards
conducting zone of the lung are composed of what on histology?
cartilage and goblet cells extend to the end of the bronchi; pseudostratified ciliated columnar cells (clear mucus from lungs) extend to the begnning of terminal bronchioles, then transition to cuboidal cells; airway smooth muscle cells extend to end of terminal bronchilies (sparse beyond this point)
respiratory zone of the lung
consists of respiratory bronchiloes, alveolar ducts, and alveoli; these are the parts that contribute to gas exchange; mostly cuboidal cells in respiratory bronchioles then simple squamous cells up to alveoli; cilia terminate in respiratory bronchioles; alveolar macrophages clear debris and participate in the immune response
what are the three types of pneumocytes?
type I, type II, and club(clara) cells
type I pneumocytes
97% of alveolar surfaces; line the alveoli; squamous, thin for optimal gas diffusion
type II pneumocytes
secrete surfactant; cuboidal and clustere; also serve as precursors to type I cells and other type II cells; type II cells proliferate during lung damage
club (clara) cells
nonciliated; low-columnar/cuboidal with secretory granules; secrete component of surfactant, degrade toxins, act as reserve cells
alveoli collpase when?
they have an increased tendency to collapse on expiration as the radius decreases (Law of Laplace)
surfactant
synthesis begins around week 26 of gestation but mature levels are not achieved until around week 35; lecithin to sphingomyelin ratio greater than 2.0 in amniotic fluid indicates fetal lung maturity.
right versus left lung lbes
the right rung as three lobes, the left has less lobes (2) and lingula
why is the right lung more common site for inhaled foreign body?
right main stem bronchus is wider and more vertical than the left
horizontal versus oblique fissure
horizontal is the top one (separates upper lobe from middle lobe) and oblique is the lower one (separates middle from upper)
Relation of pulmonary artery to the bronchus at each lung hilum
RALS; right anterior, left superior
Structures perforating the diaphragm
T8: IVC, T10: esophagus, vagus, T12: aorta, thoracic duct, azygous vein (red, white and blue); I ate 10 eggs at 12
diaphragm innervation
C3, C4, C5 (phrenic nerve); pain from the diaphragm irritation can be referred to shoulder (C5) and trapezius ridge (C3, C4)
the common carotid bifurcates where
C4