respiratory- alveolar ducts to the end Flashcards
what is the general function of the alveolar ducts and alveolar sacs and alveoli?
gas exchange
alveolar type 1=
type 1 pneumocyte
how much of the alveolar surface is type 1?
95%
what is the general function of alveolar type 1?
gas exchange
what type of cells are alveolar type 1?
squamous cell types with zona occludens btw cells
what cell type is alveolar type II/type II pneumocyte?
cuboidal
what are the functions of the alveolar type II/ pneumocyte?
1 stem cell for alveolar type I and II
2 produce pulmonary surfactant
3 produce lysozymes
what is another name for an alveolar macrophage?
dust cells
alveolar macrophage/ dust cells develop from?
monocytes
what cells clean septal walls using phagocytosis and also produce lysozymes?
alveolar macrophage/ dust cells
what is the region between 2 alveoli?
interalveolar septum
the interalveolar septum contains?
alveolar type I and II cells continous capillaries fibroblasts basal lamina small amounts of CT with many elastic fibers
what is the region where oxygen and CO2 pass between the air and blood?
blood-gas barrier
what are the 4 parts of the blood-gas barrier beginning with alveoli?
pulmonary surfactant
alveolar type I
fused basal lamina
endothelial cells of the capillary
what allows for the most efficient gas exchange?
blood-gas barrier
which ganglia provide fibers which will relax bronchial smooth muscle and result in bronchiodilation?
thoracic sympathetic chain ganglia
which fibers will cause paradoxical response of constricting pulmonary blood vessels by stimulating the smooth muscle in the tunica media?
sympathetic fibers
what nerve provides parasympathetic fibers which will contract bronchial smooth muscle resulting in bronchoconstriction?
vagus nerve
when there is a chronic exposure to irritants and metaplasia in the upper respiratory tract what cells and glands increase and decrease?
- goblet cell numbers increase causing increased mucus
- ciliated columnar cell numbers will decrease so congestion increase
- seromucus glands increase so more fluid
with much coughing patches of what develop instead of respiratory epithelium?
stratified squamous
which cell type is not present in adequate numbers of infants with RDS?
type II
what is another name for respiratory distress of the newborn?
hyaline membrane disease
what is the cause of RDS?
too few mature alveolar type II cells
what are 2 treatments for RDS?
artificial surfactant and CPAP
glucocorticoids given before birth
what is emphysema?
decrease in elastin so a decrease in alveolar elasticity
reduced surface area for gas exchange
is emphysema reversible?
no
what are the 2 causes of respiratory damage or disease?
inflammation
genetic condition
what is the protein that protects elastic fibers?
alpha 1 antitrypsin
secretion of elastase does what to elastic fibers?
damages