digestive system- stomach Flashcards
what is the surface epithelium of the stomach?
simple columnar
what are the 2 cell types in the mucosa of the stomach?
surface mucosa
regenerative cells
what are the 2 fx of the surface mucous of the stomach?
produce thick mucus
secrete bicarbonate ions
what is the lamina propria of the stomach made of?
loose vascular CT present in small amounts btw glands
where is the arteriovenous anastomosis located?
submucosa of the stomach
is the submucosa of stomach vascular or avascular?
highly vascular
what is the fx of the submucosa of the stomach?
shut down activity and secretion fast
where is the submucosal (meissner’s) plexus located?
next to inner circular layer
what is the fx of the submucosal (meissners) plexus of the stomach?
influence mucosa
what are the 3 layers of the muscularis externa of the stomach?
innermost oblique- sometimes
middle circular- well developed
outer longitudinal- thin
where is the myenteric (auerbach) plexus of the stomach located?
btw circular and longitudinal layers of ms
what is the fx of the myenteric (auerbach) plexus of stomach?
stimulate muscularis externa
is the stomach covered by serosa or adventitia?
all serosa (ME) no adventitia
what are the 3 regions of the stomach?
cardiac
gastric (fundus and body)
pyloric
what are the cell types of the cardiac region of the stomach?
primarily surface mucous
some neck mucous
few DNES and parietal cells
NO chief cells!
which is the smallest region of the stomach containing much mucus?
cardiac
what is the only region of the stomach without chief cells?
cardiac
name the surface epithelium of the stomach?
simple columnar
what type of muscle is found in the ME middle 1/3 of the esophagus?
mix of skeletal and smooth muscle
esophageal proper glands are found in which esophagus layer?
submucosa
where do the gastric glands extend?
from gastric pit to muscularis mucosa
what are the 3 regions in a gastric (zymogenic) gland?
isthmus
neck
base
what protects mucosa from auto digestion and the rougher components of chyme?
isthmus surface mucosa
what produces thick, visible mucus that traps bicarbonate ions?
surface mucus of isthmus
what is another name for DNES cells?
enteroendocrine cells
what are the 3 types of DNES cells in stomach?
type D
type EC
type G
which type of DNES cells in the stomach produce somatostatin, inhibit release of hormones by nearby DNES cells and HCL release?
type D
which type of DNES cell produces serotonin and substance P and increase gut motility?
type EC
which type of DNES cell produces gastrin, stim HCL and pepsinogen, gastric motility and regenerative cells in body of stomach?
type G
what things stimulate type G?
coffee, gastrin, alcohol, AA
how long do the neck mucous cells of the gastric region live?
6 days
what type of mucous do neck mucous cells produce?
soluble less alkaline mucous
what is the fx of the neck mucous cells?
lubricate gastric contents
which neck cells are odd columnar cells with intracellular canaliculi?
parietal cells
how long do parietal cells of neck live?
150-200 days
what produces HCL?
parietal cells
what is necessary for B12 absorption?
gastric intrinsic factor
what produces gastric intrinsic factor?
parietal neck cells
what does chronic gastritis sometimes lead to?
pernicious anemia
low # of ____ can lead to low amounts of intrinsic factor
parietal cells
how many DNES cells does the neck of the stomach have?
few
what are the 3 types of base cells?
chief (zygomatic) cells
Parietal cells
DNES cells
what do chief cells of the base of the stomach produce?
primarily pepsinogen and some gastric lipase
how long do chief cells live?
60-90 days
what region is deeper pits with very twisted and branched pyloric glands?
pyloric
what cell types are in the pyloric region
primarily surface mucus, DNES and parietal
some neck mucous
what stomach cell produces IF?
parietal
what stomach cell produces thick mucus?
surface mucus
what stomach cell produces pepsinogen?
chief cells
what cell produces HCL?
parietal
what produces a more soluble, slightly acidic mucus?
neck mucous
what produces gastrin?
DNES
what cells produce gastric lipase?
chief
which layer within the ME is not always present?
oblique
name surface epithelium of stomach
simple columnar
what are the cell types of the neck of the stomach?
mucous cells
regenerative cells
parietal cells
DNES cells
what are the cell types of the pyloric region?
primarily surface mucus
DNES
parietal
some neck mucous that also produce some lysozyme