Respiratory Flashcards
Albuterol / Ventolin
Classification
Adrenergic
MOA
Treats bronchospasms in patient with reversible obstructive airway disease. Binds to the beta 2 receptor causing smooth muscle relaxation
Indications
Relief from bronchospasms
Contraindications
Hypersensitivity
Dosage/ Route of administration
Inhaler 1-2 inhalations every 4-6 hours (90-180 meg)
2.5 mg diluted in 3 ml of inhalation saline over 5-15 minutes Neb
Aminophylline / Phyllocontin
Classifications
Bronchodilator
MOA
binds to the beta 2 receptor, smooth muscle relaxation
Indications
Reversible airflow obstruction, Asthma, Emphysema, Chronic bronchitis
Contraindications
Hypersensitivity, hypersensitivity to theophylline, liver disease, hypothyroid
Dosage/ Route of administration
250- 500 mg/ D5W infused at 5-10 mg/kg/hour
5 -mg/kg IV over 20-30 mins followed by 0.4 mg/kg/hour
Atropine / Atropen
Classification
Anticholinergics belladonna alkaloid
MOA
Competitive Antagonist for the muscarinic receptor
Indication
Bradyarrhythmias, Organophosphate poisoning
Contraindication
Hypersensitivity
Dosage/ Route of administration
0.5 mg push IV may repeat every 3 to 5 minutes up to 3 mg max for bradycardia
2- 6 mg for organophosphate poisoning
Cetacaine Spray / Hurricane Spray
Classification
Topical Mucosal Anesthetic
MOA
Blocks nerve conduction on the mucosal membrane and also blocks gag reflex
Indications
Intubation, Nasal Intubation, pain management and gag reflex
Contraindications
Hypersensitivity
Dosage/ Route of administration
200 mg 1 second or 1 spray
Epinephrine / Adrenalin
Classification
Adrenergic, Sympathomimetic
MOA
Stimulates both Alpha and Beta 1 and 2 receptor, sympathomimetic increases chronotropy,dromotropy, inotropy, automaticity, is an antagonist of histamines relaxes smooth bronchial muscles reversing anaphylaxis
Indications
Cardiac arrest, anaphylaxis, bradycardia, refractory Asthma
Contraindication
Hypersensitivity, Pre Existing tachydysrhythmia,hemorrhagic shock, hypovolemic shock, hypertension,active labor
Side Effect
Anxiety, headache, nervousness, fear, palpitations, sweating, nausea, vomiting, pale skin, shortness of breath, dizziness, weakness, tremors
Untoward effect
Increased breathing difficulty, hypertension, blurred vision, confusion, chest pain, uneven heartbeat, seizures
Cautions
Injection into the wrong area can cause gangrene and tissue necrosis
Dosage/ Route of administration
Refractory asthma, Anaphylaxis 0.3mg- 0.5 mg (1:1000) IM
Cardiac arrest 1 mg (1:10000) IV/IO every 3-5 minutes
Bradycardia, profound hypotension 0.05- 0.1 mg (1:10000) slow IV push
Post arrest infusion 0.1- 0.5 mcg/kg/min with a max of 30 mcg/min mix 1 mg in 250 ml
Ett 2- 2.5 mcg diluted in 10 ml in normal saline
Etomidate / Amidate
Classification
General Anesthetic, Hypnotic
MOA
Hypnotic used for the induction of the anesthesia lacks analgesic activity has minimal cardiovascular effect has a rapid onset usually within one minute binds to the GABA receptor
Indication
Sedation for intubation Cardioversion, and simple procedures
Contraindication
Hypersensitivity, sepsis, younger than 10 nursing mothers
Side effects
Hypertension, laryngospasm, hyperventilations
Untoward effects
Tachycardia, nausea vomiting
Cautions
Impairment of fertility
dosage/ Route of administration
0.2-0.6 mg./kg IV over 15-30 seconds IV
Furosemide / Lasix
Classification
Loop diuretic
MOA
Blocks absorption of sodium chloride, water and potassium at the loop of henle causes profound increased urinary output
Indications
Edema associated with CHF, cirrhosis of the liver renal disease, hypertension
Contraindications
Hypersensitivity, hypersensitivity to sulfa, hypotensive, Known electrolyte imbalance
Dosage
Hypertension 40 to 80 mg no faster than 20 mg min IV,IO
CHF 0.5-1 mg/kg IV
Ipratropium Bromide / Atrovent
Classification
Anticholinergic
MOA
Antagonizes action of the acetylcholine on bronchial smooth muscles in the lungs causing bronchodilation
Indications
Maintenance treatment of bronchospasms COPD, Chronic bronchitis, Emphysema, Asthma
Contraindications
Hypersensitivity, Hypersensitivity to Atropine, soy peanuts
Side effects
Headache, dizziness, nausea, dry mouth, tremors
Untoward effects
Chest pain, pounding heartbeats, Hypertension, Swelling ankles or feet, painful or difficulty urinating, low potassium
Dosage/ Route of administration
500 mcg nebulizer typically with Albuterol
Lidocaine jelly / Lidocaine hydrochloride
Classification
Topical local anesthetic
MOA
Stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses
Indications
Anesthetic, lubricant for intubation
Contraindications
Hypersensitivity
Side effects
Possible tube obstruction from dried jelly
Untoward effects
Airway obstruction
Dosage/Route of administration
Generous amount of jelly before intubation
Magnesium Sulfate
Classification
Sulfate
MOA
Physiological calcium channel blocker causing relief from hypotension, stops preterm labor, bronchodilator, Blocks or decreases acetylcholine receptors stopping seizures activity and dysrhythmias due to low magnesium levels
Indication
Preterm labor, seizures, hypomagnesemia, bronchospasms, Tetany, hypotension
Contraindications
hypersensitivity, Shock, Third degree AV node block, GI obstruction, Nursing mothers history of myocardial damage, Bradycardia
Side effects
Fainting, nausea, Hypermagnesemia
Untoward effects
Respiratory depression
Dosage
Respiratory 2g over 20 IV,IO diluted in 100ml
Torsades 1-2g diluted 100 ml over 5-60 min follow with infusion
Eclampsia 4-6 mg IM or 1-2g diluted in 100 ml over 30 min.
Phenylephrine / Neo synephrine spray
Classification
Nasal decongestant, Sympathomimetic
MOA
Stimulates Alpha 1 receptors causing vasoconstriction
Indications
Nasal intubation
Contraindications
Hypersensitivity
Side effects
trouble sleeping, trembling, nervousness headache nausea, vomiting
Untoward effects
Fast or irregular heart rate, pounding pulse, chest tightness
Dosage
1 to 2 sprays per nare
Oxygen / O2
Classification
Medical gas
MOA
Reverse hypoxia, increases hemoglobin saturation
Indication
Hypoxia, poor perfusion
Contraindications
Paraquat poisoning
Side effects
Dry out mucous membrane
Untoward effects
none
Dosage/ Route of administration
3-25 LPM via NC, non rebreather, CPAP, BVM, venturi mask, intubation tube
Propofol / Diprivan
Classification
General Anesthesia
MOA
Binds to the GABA receptor used for introduction of anesthesia decreasing the rate of dissociation of the GABA receptor
Indication
Procedural sedation, anesthesia
Contraindication
Hypersitivity, egg and soy products
Side effect
dizziness , nausea, pain at injection site, dark urine
Untoward effect
Breathing problems, changes in vision, fast of irregular heart beats
Dosage
Dose 1.5-3 mg/kg
Infusion 25-75 mcg/kg/min
(Steroids)
Name Baycadron Solu-Cortef Solu-medrol Deltasone
Trade Name Dexamethasone Hydrocortisone Meththylperdnisolone Prednisone
Classification
Steroid
MOA
Intermediate-acting steroids that inhibits production of substances that cause inflammation and inhibits synthesis of pro-inflammatory enzymes
Indication
Bronchospasms, anaphylaxis, croup
Contraindication
Hypersensitivity to sulfa, Fungal infection, Cushioning syndrome, CHF, chicken pox, Hypertension, seizure, thrombocytopenia
Side effects
Headache, confusion, vomiting weight gain
Untoward effects
Mood changes, hives rash
Dosage
Dexamethasone Asthma 0.6-1 mg/kg
Allergic reaction 4-10 mg IV/IM
Hydrocortisone 100mg IV,IM,IO
Meththylperdniolose 125 mg IV,IM,IO
Prednisone 5-60 PO
Racemic epi / Racemic epinephrine
Classification
Sympathomimetic
MOA
Binds to both alpha and beta receptor bronchodilation decreased mucous membrane section relieves subglottic edema
Indication
Croup, bronchospasms and subglottic edema
Contraindication
Hypepertension, hypersensitivity, epiglottis
Side effects
anxiety, dizziness, headache, hypertension
Untoward effects
Tachycardia,restlessness
Dosage/ Route of administration
11.25 mg in 2.5 ml of NS Neb