Respiratory Flashcards
Which class is montelukast [Singulair®] under?
leukotriene inhibitor
What are the indications for montelukast?
asthma, bronchospasm & ALLERGIC RHINITIS!!!
leukotrienes bind with what to produce an immune response?
endogenous ligands (LTC/D/E 4s) from mast cells and eosinophils
Does montelukast have any ocular side effects?
NO!
Which drug class is albuterol a part of?
ß-2-agonists
Albuterol is used for asthma and bronchospasm, like montelukast, and WHAT OTHER?
COPD
What does B-2-agonist do to the smooth muscles of your respiratory system?
relaxation!
Which drugs cause a prolonged QT interval? (6)
ß-2 agonist (albuterol)*
advair diskus (fluticasone & salmeterol)*
furosemide*
HCTZ; hychlorothiazide*
trazadone*
quetiapine*
*macrolides/erythromicins, and some other antibiotics
Which two drugs make up advair diskus®?
fluticasone (steroid)
salmeterol (ß-2-agonist)
What are some severe ocular side effects of advair diskus®?
cataracts, glaucoma and elevated IOP
Which class is mometasone [Nasonex®]?
steroidal anti-inflammatories
Which ocular side effects are caused by mometasone?
glaucoma and elevated IOP
Which drug are these contraindications for?
- TB infection
- nasal septal ulcer, recurrent epistaxis
- ocular HSV infection, glaucoma, cataracts
- vision changes
mometasone
