Hormones Flashcards
Which drug class have:
levothyroxine [Synthroid®, Levoxyl®]
liothyronine
Thyroid therapies: hypothyroidism
Which drug class include:
propylthiouracil (PTU)
methimazole [Tapazole®]
thyroid therapies: hyperthyroidism
Which drug class include:
estrone [Menset®]
estradiol
mestranol
menopausal therapy
LDL/HDL levels are increased with ________ therapy.
hormone replacement therapy; HRT
Which hormone can cause ptosis, diplopia, and EOM paresis?
hypothyroid therapy; levothyroxine or liothyronine
Which two types of therapy might cause the patient to become contact lens intolerant?
Menopausal therapy (estradiol) or contraception (Yaz®)
Which two drugs make up Yaz®?
drospirenone and ethinyl estradiol
How does Yaz® work?
Suppresses LH & FSH
inhibits ovulation
alters cervical mucus and endometrium
Which drug includes a black box warning of: CV events enhanced if smoking?
Yaz®
Which therapy/drug comes with a black box warning of: endometrial cancer stroke DVT MI invasive breast cancer
hormone replacement therapy; menopausal therapy; estradiol, estrone, & mestronaol
Which SERMs are indicated for breast cancer?
Tamoxifen [Soltamox®]
clomiphene
raloxifene
What does SERM stand for?
selective estrogen receptor modulators
Which drug class is Tamoxifen and describe its mechanism of action.
SERMs
binds to estrogen receptors; different effect on different tissues
What unique effect do SERMs (tamoxifen) have on cyclosporine, systemic steroids and oxycodone levels?
increases these levels; first time we see something increase cyclosporine’s levels.
