Respiratory 2 Flashcards
Acute Respiratory Failure
Not a disease but a symptom
Hypoxemia occurs due to inadequate O2 transfer
Hypercapnia occurs due to insufficient CO2 removal
Hypoxemic Failure
a) What is it?
b) causes?
c) patho
a) Oxygen failure
PaO2 <60 with FiO2 60%
b) ARDS
Pneumonia
Massive PE
Toxic inhalation
Cardiac anatomic shunt
Shock
c) Alveolar hypoventilation
Shunt
Mismatch VQ
Hypercapnic Failure
a) what is it?
b) causes?
a) Ventilation failure
PaCO2>45 with pH< 7.35
↑CO2 production
Decrease alveolar ventilation
b) Asthma, COPD, CF
CNS-opioid overdose, head injury
Chest trauma, kyphoscoliosis, pain, obese
MS, ALS, GB
Clinical Manifestations
Restlessness
Confusion
(think O2 is not going to brain that well)
Tachypnea,Prolonged expiration, retraction
dysrhythmias, HTN, tachycardia
inability to talk in complete sentences(true SOB)
Diagnostic Studies
ABG, SpO2
ECG
Hemodynamic monitoring, SvO2
P/F ratio (PaO2 ÷ FiO2-oxygen content when inhales)
norml = > 400; acute lung injury/ARDS < 300
bad or good?
a) PaO2= 101
FiO2= 21%
b) PaO2= 85
FiO2= 40%
a) good
b) bad
Collab Care
O2 therapy (PaO2 ≥ 60, SaO2 ≥ 90)
Positioning HOB ≥ 45 º(30-45º)
Monitor trends/ABGs
incentive spirometry
How to use incentive spirometry
Sit straight up
Before you use the spirometer, breathe out normally
Place the mouthpiece in your mouth. Make sure your lips are closed tightly
Breathe in slowly and as deeply as you can
Hold your breath for 3–5 seconds,
Remove the mouthpiece from your mouth and breathe out normally.
Rest for a few seconds, then repeat the steps 10 or more times.
Do this every 1–2 hours when you are awake.
After each set of 10 deep breaths
Optimize Oxygen Delivery
how?
blood administration
fluid administration,
PEEP(pressure applied by the ventilator at the end of each breath)
Decrease Oxygen Demand
how?
rest periods
quiet/restful environment
treat fever
treat pain
Nutritional support
What is ARDS?
NO Evidence of Heart Failure
Sudden progressive
Characterized by:
Acute onset
Decreased compliance, “stiff/small lungs”
ARDS Criteria
Mild ARDS ?
Moderate ARDS?
Severe ARDS?
Acute onset (within one week of insult)
Bilateral infiltrates (CXR)
Refractory hypoxemia
P/F ratio <300 mm HG
P/F ratio < 200 mmHg
P/F ratio ≤ 100 mmHg
Causes
Direct lung injury
Indirect lung injury (sepsis most common cause)
Systemic inflammatory response syndrome (SIRS)
Multiple organ dysfunction syndrome (MODS)
Emerging causes
e-cigarettes and vaping
Drug-induced- chemotherapeutics and immunotherapies
Viral Pneumonia- H1N1influena, COVID
Clinical Presentation
Tachypnea, restlessness
Excessive accessory muscle use, crackles
Non-cardiogenic pulmonary edema
Crackles
Refractory hypoxemia
PaO2 < 60 mmHg on FiO2 > 50%
Increase FiO2 which does not increase PaO2