Respiratory Flashcards
COPD
chronic obstructive pulmonary disease
progressive development of airflow limitation
overinflated alveoli
Ventilation (V)
Air exchange
Inhalation and exhalation
O2 in CO2 out
Perfusion (Q)
Gas exchange - at the capillary level, blood flow to tissues and organs
V/Q mismatch
adequate inhalation but can’t extract O2 or bringing blood with no O2 - lead to hypoxia - lead to respiratory failure
V/Q mismatch causes:
obstructed airway
obstructed blood flow in lungs e.g. clot
Resp failure causes
- CNS causes: depression of drive to breath e.g. overdose
- Alveoli abnormalities
-Airway instructions: COPD, asthma - PNS disorders: resp muscle and chest wall weakness
Respiratory Failure
result of one or more diseases involving the lungs
resp system can’t maintain gas exchange
Type 1 resp failure
impaired gas exchange at alveo-capillary level due to lung tissue damage preventing oxygenation
hypoxia - low O2
Type 2 resp failure
Occurs when alveolar ventilation is insufficient to excrete CO2 - leading to increased CO2 in blood
Increased CO2 leads to high acidity in the blood
Hypercapnia
High CO2 levels in the blood
Normal PaO2 range
80-100mm/Hg
Type 2 resp failure PaCO2 range
greater than 50mm/Hg
Type 1 Resp failure causes
asthma
pulmonary oedema
ARDS
COVID
pneumonia
Type 2 Resp failure causes
COPD
chest abnormalities
resp muscle weakness
chronic bronchitis
emphysema
Resp failure signs and symptoms
- gradual changes in PaO2 or PaCO2
- Dyspnoea
- Tachypnoea
- Restless
- Confusion
- Central Cyanosis
- Tachycardia
- Pulmonary hypertension
- Loss of conscious