Respiration Flashcards
Whats the formula for respiration?
C6H12O6 + 6O2 —— 6H2O + 6CO2 + Energy
What is the definition of respiration?
The release of chemical potential energy from organic molecules
What is ATP
Phosphorylated nucleotide with 3 phosphate
What is the first stage of respiration?
Glycolysis
What are the stages of glycolysis
- Phosphorylation
- becomes bisphosphate
- requires 2 ATP - Lyis
- split hexose bisphosphate to triose phosphate - Phosphorylation
- go from triose phosphate to triose bisphosphate - Oxidation
- triose bisphosphate oxidised to pyruvate
- Hydrogen is removed which is done by dehydrogenase
- H reduced NAD
Where does glycolysis take place?
Cytoplasm
Is glycolysis anaerobic or aerobic?
Both
Whats the equation for glycolysis?
C6H12O6 —- 4ATP + 2NADH + 2 Pyruvate
Where is pyruvate moved after glycolysis?
Into mitochondria by AT
What are stuctures in mitochondria?
Matrix - space within membrane. Contain enzymes and DNA
Cristae - folded membrane, SA for oxidative phosphorylation
Outer Mitochondrial space - creates cellular compartments for aerobic
Inter membrane Space - where protons are pumped
Inner mitochondrial membrane - contain electron transport chain
What does oxidative decarboxylation take place?
In matrix
What enzyme removes CO2 from pyruvate?
Decarboxylase
What other molecule is removed when CO2 is removed?
H which then reduced NAD
What molecule is made when CO2 is removed from pyruvate?
Acetyl
What is the final product of the link reaction?
Acetyl Coenzyme A
Where does the Krebs cycle take place?
Matrix
What are products of krebs cycle?
oxaloacetate
How many carbons are in citric acid?
6C
How many carbons are in oxaloacetate?
4C
What are the stages of the krebs cycle?
- Acetyl CoA combine with oxaloacetate
- this releases CoA
- makes citrate - Citrate is converted back to oxaloacetate
- 2 CO2 release
- 3NADH made
- FADH2 made - One molecule ATP made
How many ATP molecules are produced from one molecule of glucose in krebs cycle?
2 as each pyruvate from glycolysis is converted to molecule of acetyl CoA which is then used in Krebs
What is krebs cyle?
Substrate level phosphorylation
What is the penultimate stage of respiration?
Oxidative phosphorylation
Where is the electron transport chain?
inner membrane of mitochondria
What are protein carriers called?
cytochrome
What are the role of NADH and FADH2?
To release protons and an electron
What chemical reaction take place between electron and cytochrome?
Reduction
What is the role of electron pairs in the electron transport chain
They move down chain and provide energy to phosphorylate ADP to ATP
What reaction occurs at the end of the chain?
e- + 2H + O — H2O
How does the final stage of respiration produce ATP
Protons are pumped to inter membrane space which produces electrochemical gradient
Protons then moved back down gradient through membrane bound enzyme
This acts as ATPase
Movement is called chemiosmosis
How many molecules of NADH and FADH2 are produced in krebs
3 NADH
FADH2
What happens to the citric acid to produce oxaloacetate
Dehydrogenation and decarboxylated
What is the definition of substrate level phosphorylation
Metabollic reaction that results in production of ATP from another phosphorylated molecule